Use of Iterative Reconstruction Method in Ultralow-dose CT for Follow-up of Patients With Intraabdominal Abscess: Comparison With Standard Dose CT
1 other identifier
observational
20
1 country
1
Brief Summary
Increasing radiation exposure by medical examinations is getting more concerns. For optimal medical imaging, reducing radiation exposure with preservation image quality is important. One of the solutions is use of iterative recontruction of CT examination. In this study, the investigators aimed to investigate the clinical feasibility of ultralow dose abdominopelvic CT with iterative reconstruction in patients with intraabdominal abscess. Patients with intrabdominal abscess usually undergo multiple CT examinations to evaluate treatment response. Therefore, ultralow dose CT can reduce unnecessary radiation exposure in these patients.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Jun 2018
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 29, 2018
CompletedFirst Submitted
Initial submission to the registry
September 17, 2018
CompletedFirst Posted
Study publicly available on registry
September 24, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 18, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
March 18, 2019
CompletedSeptember 29, 2020
September 1, 2020
9 months
September 17, 2018
September 27, 2020
Conditions
Outcome Measures
Primary Outcomes (1)
Score of subjective image quality of CT image
Score of subjective image quality of CT images consists of overall subjective image quality, noise, diagnostic ability, and artifact.
1 month
Secondary Outcomes (1)
Effective radiation dose: CTDIvol(volume CT dose index), DLP(dose length product), effective dose(DLPx0.015)
1 month
Study Arms (1)
Abscess
Patients group with abdominal abscess
Interventions
In the patient cohort with abdominal abscess, ultralow dose abdominopelvic CT will be performed as a follow-up protocol. Ultralow dose CT has approximately 80\~90% reduced radiation dose compared to standard dose CT.
Eligibility Criteria
Patients with suspected abdominal abscess from a tertiary care clinic.
You may qualify if:
- patients who underwent standard dose CT for suspected intraabdominal abscess
- patients who need follow-up CT to evaluate treatment response of abscess 3) Adult patient, 4) patients who agreed this study protocol
You may not qualify if:
- pregnancy
- patients with poor renal function (GFR \< 30 mL/min/1/73m2)
- Patients who have allergy to CT contrast media
- Patients who are not cooperative (e.g., dementia)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine
Seoul, 03722, South Korea
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
September 17, 2018
First Posted
September 24, 2018
Study Start
June 29, 2018
Primary Completion
March 18, 2019
Study Completion
March 18, 2019
Last Updated
September 29, 2020
Record last verified: 2020-09
Data Sharing
- IPD Sharing
- Will not share