NCT03680950

Brief Summary

A monitoring system was developed for detecting upper gastrointestinal (UGI) rebleeding. This system consists of (1) a tiny endoscopy, (2) a wearable device, and (3) a software. The endoscopy is inserted to UGI tract via nasal cavity and then stayed there for 3 days. The wearable device is set to regularly receive the pictures from the endoscopy and sent to the software, which is able to automatically analyze whether the rebleeding occurs. This study aims to test the feasibility and efficacy of the monitoring system.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
18

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2018

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 17, 2018

Completed
4 days until next milestone

First Posted

Study publicly available on registry

September 21, 2018

Completed
21 days until next milestone

Study Start

First participant enrolled

October 12, 2018

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 12, 2020

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 30, 2020

Completed
Last Updated

June 16, 2020

Status Verified

May 1, 2020

Enrollment Period

1.4 years

First QC Date

September 17, 2018

Last Update Submit

June 14, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Time to detection of upper gastrointestinal rebleeding between the upper gastrointestinal monitoring system vs. the current monitoring index.

    The real-time upper gastrointestinal monitoring system is compared with the current monitoring index. The efficacy is estimated by which monitoring method finding the upper gastrointestinal rebleeding first.

    3 days

Secondary Outcomes (1)

  • The accuracy of upper gastrointestinal rebleeding detection between the upper gastrointestinal monitoring system vs. the current monitoring index.

    3 days

Study Arms (1)

Upper Gastrointestinal Monitoring System

EXPERIMENTAL

Participants who meet criteria of enrollment and is willing to join in this study will wear a real-time upper gastrointestinal monitoring system for checking whether upper gastrointestinal rebleeding occurs continuously for 3 days.

Device: Upper Gastrointestinal Monitoring System

Interventions

Participants will wear a monitoring system consisting of a tiny endoscopy and a mobile device. The endoscopy is inserted to upper gastrointestinal tract via nasal cavity and the mobile device is set to take and send images from the endoscopy to a server for analyzing if the abnormal condition occurs.

Upper Gastrointestinal Monitoring System

Eligibility Criteria

Age20 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • "Rockall" score ≧3

You may not qualify if:

  • Pregnant woman;
  • Behavioral disorder;
  • Major cognitive-perceptual deficit;
  • The person who has a nasogastric (NG) tube;
  • Other deficits or disorders that are not suitable for NG insertion;
  • Participants who need to take MRI scan.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

National Cheng Kung University Hospital

Tainan, 704, Taiwan

Location

MeSH Terms

Conditions

Gastrointestinal Hemorrhage

Condition Hierarchy (Ancestors)

Gastrointestinal DiseasesDigestive System DiseasesHemorrhagePathologic ProcessesPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 17, 2018

First Posted

September 21, 2018

Study Start

October 12, 2018

Primary Completion

March 12, 2020

Study Completion

April 30, 2020

Last Updated

June 16, 2020

Record last verified: 2020-05

Locations