Atrial Function and Supraventricular Arrhythmia of the Veteran Athlete.

NCT03665324 | Completed

• 1 other identifier: 35RC17_3066
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Supraventricular arrhythmias (including atrial fibrillation) are the most common arrhythmias of the veteran athlete and have a major impact in terms of morbidity and mortality. Although moderate sports practice has been shown to decrease the occurrence of these arrhythmias, it has also been shown that very intense athletic activity is associated with an increased risk of developing atrial fibrillation. The pathophysiological mechanism is not clearly understood. However, it has already been shown that intensive sports practice leads to electrical and morphological atrial remodeling, which could be the cause of the occurrence of supraventricular arrhythmias for these athletes. For sedentary patients, two major tools predict the risk of the onset of supraventricular arrhythmia: the electrocardiogram (ECG) and transthoracic echocardiography (ETT), particularly with the study of atrial function by the analysis of myocardial deformities.

Conditions

Supraventricular Arrhythmias

Keywords

Supraventricular arrhythmias; veteran athlete; ECG; ETT

Outcome Measures

Primary Outcomes (1)

• Study of atrial function by analysis of myocardial strain.

  Myocardial strain in extracted from ETT and compared between the two groups.

  At the inclusion day

Study Arms (2)

Veteran athletes with Supraventricular arrhythmias

Subjects who consulted in the Sports Medicine Department between January 1, 2010 and January 1, 2017 Veteran athletes (age\> 35 years) with documented paroxysmal supraventricular arrhythmias.

Other: Evaluation of the relationship between atrial remodeling evaluated by ECG and ETT with the occurrence of supraventricular arrhythmias

Veteran athletes without supraventricular arrhythmia

Subjects who consulted in the Sports Medicine Department between January 1, 2010 and January 1, 2017 Veteran athletes (age\> 35 years) without documented supraventricular arrhythmia.

Other: Evaluation of the relationship between atrial remodeling evaluated by ECG and ETT with the occurrence of supraventricular arrhythmias

Interventions

Evaluation of the relationship between atrial remodeling evaluated by ECG and ETT with the occurrence of supraventricular arrhythmias OTHER

Subjects will be retrospectively retrieved from the Sport Medicine Service of Rennes University Hospital database. Medical data will then be collected from the athletes' medical records. The ECG present in the medical file will be reinterpreted to obtain the resting heart rate, the amplitude of the P wave, the morphology of the P wave and the duration of the PR space. The data from the stress test will be found from reports in the medical records: resting heart rate, maximum heart rate, sustained peak load, arrhythmia during the test. ETTs will be retrieved from the local server. They will be reinterpreted to collect anatomical and functional cardiac data necessary for the study.

Veteran athletes with Supraventricular arrhythmias; Veteran athletes without supraventricular arrhythmia

Eligibility Criteria

• Age: 35 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Veteran athletes who consulted in the Sports Medicine Department between January 1, 2010 and January 1, 2017

You may qualify if:

• Supraventricular arrhythmia group : Veteran athletes with documented paroxysmal supraventricular arrhythmias.
• Control Group : Veteran athletes without documented supraventricular arrhythmia.

You may not qualify if:

• Any cardiopathy (valvulopathy, coronary heart disease, etc.).
• Minor patients,
• Major patients subject to legal protection (legal safeguards, guardianship)
• Persons deprived of their liberty
• Patients opposed to the use of their personal data.

Sponsors & Collaborators

• Rennes University Hospital: lead

Study Sites (1)

Rennes University Hospital

Rennes, 35000, France

Location

Study Officials

• frederic SCHNELL, MD

  Rennes University Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 5, 2018
• First Posted: September 11, 2018
• Study Start: April 28, 2017
• Primary Completion: May 15, 2017
• Study Completion: May 15, 2017
• Last Updated: September 11, 2018

Record last verified: 2018-09

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)