The Evaluation of the Deepithelialized Gingival Graft Healing

NCT03665272 | Completed

• 1 other identifier: Zeck
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study was to compare of the effects of different fixation methods on deepithelialized gingival graft wound healing. Laser doppler flowmetry method was used to determine for blood perfusion changes. 40 patients were devided into two groups randomly and deepithelialized gingival graft procedure was performed and healings were evaluated by laser doppler flowmetry.

Conditions

Wound Heal

Outcome Measures

Primary Outcomes (1)

• deepithelialized gingival graft blood perfusion change

  Blood perfusions (units) were measured by laser doppler flowmetry

  measurements were performed at the day of surgery, 1, 3 and 7 days.

Secondary Outcomes (1)

• Deepithelialized gingival graft recipient bed pain changes

  measurements were performed at 1, 3 and 7 days post surgery.

Study Arms (2)

fixation by tissue adhesive

EXPERIMENTAL

In this group, deepithelialized gingival grafts were fixed by tissue adhesive without any suture.

Procedure: deepithelialized gingival graft fixation

fixation by sutures

EXPERIMENTAL

In this groups, deepithelialized gingival grafts were fixed by 4.0 round vicryl sutures.

Procedure: deepithelialized gingival graft fixation

Interventions

deepithelialized gingival graft fixation PROCEDURE

one group's deepithelialized gingival graft fixed by sutures and other one's by tissue adhesive.

fixation by sutures; fixation by tissue adhesive

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• to 65 years of age
• systemically healthy
• inadequate amount or absence of keratinized gingiva on the labial side of the lower incisor region
• no restorations on the lower incisor region
• no mucogingival surgical history in the lower incisor region
• no periodontal treatment within the previous year
• no systemic antibiotics taken for 6 months before the study
• not pregnant or lactating
• no-smoking

You may not qualify if:

• lower 18 and upper than 65 years of age
• systemical disease
• adequate amount of keratinized gingiva on the labial side of the lower incisor region
• restorations on the lower incisor region
• mucogingival surgical history in the lower incisor region
• periodontal treatment within the previous year
• systemic antibiotics taken for ‡6months before the study
• pregnancy or lactating
• smoking history or current smokers

Sponsors & Collaborators

• TC Erciyes University: lead

Study Sites (1)

Zekeriya Taşdemir

Kayseri, Melikgazi, 38039, Turkey (Türkiye)

Location

Study Officials

• zekeriya taşdemir, phd

  TC Erciyes University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Pricipal investigator

Study Record Dates

• First Submitted: September 5, 2018
• First Posted: September 11, 2018
• Study Start: January 10, 2018
• Primary Completion: September 3, 2018
• Study Completion: September 3, 2018
• Last Updated: September 11, 2018

Record last verified: 2018-09

Locations

TU (1)