>The Purpose of This Study Was to Determine Whether Consuming a 100-mL Cup of Coffee is Effective in Preventing or Reducing Postoperative Ileus After Laparotomy of Benign Gynecological Patients

NCT03660267 | Completed

• 1 other identifier: coffeeaof
• Study Type: interventional
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

Comparison of the effectiveness coffee (with or without caffeine) ingestion and water for reducing the duration of Postoperative ileus after Laparotomy of Benign Gynecological Patients

Conditions

Effects of Coffee Ingestion on Recovery of Bowel Function

Keywords

Benign Gynecologic Operation; Coffee Ingestion; Recovery of Bowel Function

Outcome Measures

Primary Outcomes (1)

• time to flatus

  measure time to first flatus after finished operation

  ึ7 day

Secondary Outcomes (2)

• time to toleration of a solid diet

  7 day

• time to defecation

  7 day

Study Arms (3)

coffee group

EXPERIMENTAL

caffeine coffee

Other: caffeine coffee

decaffeinete coffee group

EXPERIMENTAL

decaffeinete coffee group

Other: decaffiene coffee

water group

EXPERIMENTAL

Other: still water

Interventions

caffeine coffee OTHER

drank 3 cups of caffeinated coffee daily (100 mL at 05:00 AM, 10:00 PM, and 15:00 PM), beginning on the morning after surgery Patients were free to drink any amount of water but no more coffee, black tea, or other form of caffeine, such as soda. Coffee was prepared with a conventional coffee machine

coffee group

decaffiene coffee OTHER

drank 3 cups of decaffeinated coffee daily (100 mL at 05:00 AM, 10:00 PM, and 15:00 PM), beginning on the morning after surgery Patients were free to drink any amount of water but no more coffee, black tea, or other form of caffeine, such as soda. Coffee was prepared with a conventional coffee machine

decaffeinete coffee group

still water OTHER

drank 3 cups of still water daily (100 mL at 05:00 AM, 10:00 PM, and 15:00 PM), beginning on the morning after surgery Patients were free to drink any amount of water but no more coffee, black tea, or other form of caffeine, such as soda. Coffee was prepared with a conventional coffee machine

water group

Eligibility Criteria

• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients were asked to participate if they were scheduled to undergo laparotomy for a benign gynecologic condition
• Ever drink coffee before
• can speak or communication Thai language

You may not qualify if:

• hypersensitivity or allergy to caffeine/ coffee 2.ever intraabdominal sugery before 3. had an active intra-abdominal malignancy, bowel perforation, pre-existing bowel disease, or a history of abdominal or pelvic irradiation.
• pregnancy woman 5.thyroid disease 6 Inflammatory bowel disease 7.liver disease 8.cardiac arrhythmia 9.history of difficult to defecation ( feces only 2 times per week) 10.after operation need to stay in ICU more than 24 hr 11.need to put Ng tube after operation

Sponsors & Collaborators

• Department of Medical Services Ministry of Public Health of Thailand: lead

Study Sites (1)

Rajavithi Hospital

Phaya Thai, Bangkok, 10400, Thailand

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 4, 2018
• First Posted: September 6, 2018
• Study Start: September 3, 2018
• Primary Completion: September 30, 2019
• Study Completion: September 30, 2019
• Last Updated: October 30, 2019

Record last verified: 2018-07

Locations

TH (1)