Exercise for Preventing the Metabolic Syndrome in Latinoamerican Amerindians

NCT03653468 | Completed DMC

• 1 other identifier: 28082018
• Study Type: interventional
• Target: 28
• Locations: 1 country
• Sites: 1

Brief Summary

Despite exercise training decrease blood fasting glicaemy in 'average' terms, there is a wide inter-individual variability after exercise training explored mainly in adults but not in adults with prediabetes comorbidities. Thus, is yet unknown the effects and influence of the concurrent training (CT) eliciting responders (R) and non-responders (NR) cases (i.e., percentage of subjects who experienced a non-change/worsened response after training in some metabolic outcomes).

Conditions

Obesity; Cardiovascular Risk Factor; Physical Activity

Outcome Measures

Primary Outcomes (3)

• Fasting glucose

  Change from Baseline in fasting glucose

  Baseline and 20-weeks immediately after the interventions ends

• Total cholesterol

  Change from baseline in Total cholesterol

  Baseline and 20-weeks immediately after the interventions ends

• Blood pressure

  Change from baseline in Blood pressure

  Baseline and 20-weeks immediately after the interventions ends

Secondary Outcomes (6)

• Body mass

  Baseline and 20-weeks immediately after the interventions ends

• Waist circumference

  Baseline and 20-weeks immediately after the interventions ends

• Fat mass

  Baseline and 20-weeks immediately after the interventions ends

• Lean mass

  Baseline and 20-weeks immediately after the interventions ends

• Heart rate at rest

  Baseline and 20-weeks immediately after the interventions ends

Study Arms (2)

Control group

NO INTERVENTION

No-exercise

Endurance training plus resistant training

EXPERIMENTAL

Concurrent training

Behavioral: Concurrent training (CT)

Interventions

Concurrent training (CT) BEHAVIORAL

The core part of each session included resistance training (RT) followed by aerobic training exercises (for 50 and 30 minutes, respectively) and was preceded and followed by a 5-minute warm-up and cool-down with callisthenic movements.

Endurance training plus resistant training

Eligibility Criteria

• Age: 30 Years - 59 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Written informed consent
• Interested in improving health and fitness

You may not qualify if:

• Cardiovascular contraindications to exercise
• History of stroke, asthma or chronic obstructive pulmonary disease, muscle-skeletal disorders
• Smoking
• A compliance rate to the exercise program ≥ 70% was required for the participants in the intervention group to be included in the statistical analyses.

Sponsors & Collaborators

• Universidad Santo Tomas: lead
• Universidad del Rosario: collaborator
• Universidad Pública de Navarra: collaborator
• Healthcare Center Tomas Rojas: collaborator
• Universidad de Los Lagos: collaborator

Study Sites (1)

Cristian Alvarez

Los Lagos, Osorno, 000000000, Chile

Location

MeSH Terms

Conditions

Obesity; Motor Activity

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Behavior

Study Officials

• Cristian Alvarez, PhD

  Universidad de Los Lagos

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Behavioral

Study Record Dates

• First Submitted: August 28, 2018
• First Posted: August 31, 2018
• Study Start: January 1, 2018
• Primary Completion: May 28, 2018
• Study Completion: August 25, 2018
• Last Updated: August 31, 2018

Record last verified: 2018-08

Data Sharing

• IPD Sharing: Will not share

Locations

CL (1)