NCT03652506

Brief Summary

During laparoscopic surgery, the abdomen is inflated with carbon dioxide for abdominal imaging and increased intraabdominal pressure affects intraabdominal structures and abdominal wall.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
90

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Aug 2018

Shorter than P25 for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 19, 2018

Completed
9 days until next milestone

Study Start

First participant enrolled

August 28, 2018

Completed
1 day until next milestone

First Posted

Study publicly available on registry

August 29, 2018

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 28, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 28, 2018

Completed
Last Updated

August 29, 2018

Status Verified

August 1, 2018

Enrollment Period

4 months

First QC Date

August 19, 2018

Last Update Submit

August 28, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • rso2

    The regional oxymetry probe will be placed in the abdominal region of the umbilicus in the middle clavicular line

    peroperative 2 hours

Secondary Outcomes (3)

  • Visual Analog Scale

    Postoperative 24 hours

  • tramadol consumption

    Postoperative 24 hours

  • additional analgesic use

    Postoperative 24 hours

Study Arms (3)

Group A

ACTIVE COMPARATOR

The regional oxymetry probe will be placed in the abdominal region of the umbilicus in the middle clavicular line before the disease operation begins.

Device: regional oxymetry probe

Group E

ACTIVE COMPARATOR

Thoracic Epidural block +The regional oxymetry probe will be placed in the abdominal region of the umbilicus in the middle clavicular line before the disease operation begins.

Device: regional oxymetry probeProcedure: Thoracic Epidural block

Group Q

ACTIVE COMPARATOR

Ultrasound guided unilateral anterior Quadratus Lumborum block +The regional oxymetry probe will be placed in the abdominal region of the umbilicus in the middle clavicular line before the disease operation begins.

Device: regional oxymetry probeProcedure: Quadratus Lumborum block

Interventions

The regional oxymetry probe will be placed in the abdominal region of the umbilicus in the middle clavicular line before the disease operation begins.

Also known as: abdominal wall tissue oxygenation
Group AGroup EGroup Q

Ultrasound guided unilateral anterior Quadratus Lumborum block with 20 ml %0.25 bupivacaine+The regional oxymetry probe will be placed in the abdominal region of the umbilicus in the middle clavicular line before the disease operation begins.

Group Q

Thoracic Epidural block with 20 ml %0.25 bupivacaine+The regional oxymetry probe will be placed in the abdominal region of the umbilicus in the middle clavicular line before the disease operation begins.

Group E

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Patients who were in the American Society of Anesthesiologists (ASA) I-III class
  • Underwent laparoscopic cholecystectomy

You may not qualify if:

  • Previous surgeon surgeon
  • Local anesthetic allergy,
  • Bleeding is a diathesis disorder
  • Mental impairment,
  • Allergic to the drugs used,
  • Patients who are not reluctant to participate in the study,
  • Presence of infection in the block area,
  • Patients whose body mass index is over 30

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Officials

  • Korgün Ökmen, M.D

    Bursa Yuksek Ihtisas Training and Research Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

korgün Ökmen, M.D

CONTACT

Burcu Metin Ökmen, M.D

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Masking Details
Participant, Outcomes Assessor
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Model Details: prospective,randomized
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

August 19, 2018

First Posted

August 29, 2018

Study Start

August 28, 2018

Primary Completion

December 28, 2018

Study Completion

December 28, 2018

Last Updated

August 29, 2018

Record last verified: 2018-08

Data Sharing

IPD Sharing
Will not share