Effects of Yoga, Strength Training and Aerobic Exercise on Cognition in Adult Cancer Survivors
1 other identifier
interventional
78
1 country
1
Brief Summary
The investigators propose to compare the effects of a 12-week, supervised, site-based group yoga intervention on cognitive function, functional fitness, and well-being in middle-aged cancer survivors. Subjects will be randomly assigned to one of three exercise conditions: a yoga group, an aerobic walking group or a strength training group. All sessions (2-3 times per week) will be led by a trained exercise leader for a total of 150 minutes of exercise each week for the 12-week intervention.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable cancer
Started Oct 2018
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
August 22, 2018
CompletedFirst Posted
Study publicly available on registry
August 28, 2018
CompletedStudy Start
First participant enrolled
October 1, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 30, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
May 30, 2020
CompletedJuly 5, 2023
June 1, 2023
1.7 years
August 22, 2018
June 30, 2023
Conditions
Outcome Measures
Primary Outcomes (1)
Cognitive Function
Participants will complete part of the NIH Toolbox measures that assess cognitive function.
Change from baseline to 12 weeks will be reported
Secondary Outcomes (1)
Cardiovascular Function
Change from baseline to 12 weeks will be reported
Other Outcomes (1)
Feasibility: Recruitment and retention rates
Baseline to 12-weeks
Study Arms (3)
Yoga Practice
EXPERIMENTALParticipants will be led through a beginner yoga course taught by a certified yoga instructor. Classes will meet twice a week for 75 minutes each for the duration of 12 weeks. Sessions will focus on yoga postures, breathing, and meditative practices and may utilize mats, blocks, belts, and blankets.
Stretching and Toning
ACTIVE COMPARATORThis 12 week, progressive stretching and toning course will aid participants in building whole body strength and flexibility by utilizing weights, chairs, mats, and various other exercise equipment. Sessions will meet three times a week for 50 minutes and will offer 'easy' and 'hard' modifications taught by an exercise leader.
Aerobic Walking
EXPERIMENTALParticipants will partake in treadmill walking that encourages them to reach a pre-determined heart rate range. Sessions will be conducted three times a week for 50 minutes, and offer participants to self-select a speed and incline to meet their target heart rate zone.
Interventions
12 weeks, total of 150 minutes of exercise per week.
Eligibility Criteria
You may qualify if:
- years of age
- Cancer diagnosis
- year since last cancer treatment (surgery, chemotherapy, and/or radiation)
- Not planning to receive treatment during study period
- Completion of Physical Activity Readiness Questionnaire (PAR-Q)
- Ambulatory and absence of health conditions that may be exacerbated by yoga, walking, or strength training
- Physician consent (if deemed necessary)
- Low-active, i.e. less than 150 minutes/week of moderate to vigorous exercise, no current yoga practice (including within last six months)
- Intention to remain in the Champaign-Urbana area over the study duration
- Willingness to be randomly assigned to one of the three groups (yoga, aerobic walking, strength training)
- Comfortable with reading, writing, and speaking English
You may not qualify if:
- Below 30 or above 70 years of age
- Cancer diagnosis of the brain
- Less than 1 year since last treatment (surgery, chemotherapy, and/or radiation) or plans to receive treatment during study
- Determined ambulatory or 'high risk' based on responses to PAR-Q
- High-active (exercising more than 150 minutes/week in the last six months)
- No consent from physician
- Intent to be away from the Champaign-Urbana area for an extended period of time during the study
- Inability to communicate effectively in English
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Illinois at Urbana-Champaign
Urbana, Illinois, 61801, United States
Related Publications (1)
Gothe NP, Erlenbach ED, Streeter SL, Lehovec L. Effects of yoga, aerobic, and stretching and toning exercises on cognition in adult cancer survivors: protocol of the STAY Fit pilot randomized controlled trial. Trials. 2020 Sep 15;21(1):792. doi: 10.1186/s13063-020-04723-2.
PMID: 32933561DERIVED
Related Links
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Neha Gothe, Ph.D., M.A.
University of Illinois at Urbana-Champaign
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- BASIC SCIENCE
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assistant Professor
Study Record Dates
First Submitted
August 22, 2018
First Posted
August 28, 2018
Study Start
October 1, 2018
Primary Completion
May 30, 2020
Study Completion
May 30, 2020
Last Updated
July 5, 2023
Record last verified: 2023-06
Data Sharing
- IPD Sharing
- Will not share