Right Ventricular Function in Heart Failure
Assessment Right Ventricular Systolic Function in Heart Failure With Preserved, Reduced and Mid-range Ejection Fraction
1 other identifier
observational
150
0 countries
N/A
Brief Summary
Only a few studies evaluated the RV systolic function in the three categories of HF, regarding the importance of understanding changes in RV function on clinical presentation and outcome; it was essential to understand the prevalence and severity of RV dysfunction among the three groups and the degree of correlation between RV with LV systolic function.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Jan 2017
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
July 1, 2018
CompletedFirst Submitted
Initial submission to the registry
August 17, 2018
CompletedFirst Posted
Study publicly available on registry
August 22, 2018
CompletedAugust 22, 2018
August 1, 2018
1.4 years
August 17, 2018
August 20, 2018
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
assessment of the RV systolic dysfunction in patients with heart failure
degree and prevalence of the RV systolic dysfunction in patients with heart failure with preserved, mid-range and decreased ejection fraction
1.5 year
Study Arms (3)
heart failure with preserved ejection fraction
heart failure with mid range ejection fraction
heart failure with reduced ejection fraction
Interventions
echocardiographic assessment of the RV and LV systolic function
Eligibility Criteria
HFpEF\>50%, HFrEF\<40% and HFmrEF \>40% and \<50%
You may qualify if:
- Adult patients of both gender who have the followiong criteria :
- (i) symptoms with or without signs of HF (ii) elevated natriuretic peptides (BNP ≥35pg/ mL or NT-proBNP≥125pg/mL) (iii) relevant structural heart disease: left ventricle hypertrophy (left ventricular mass index ≥115 g/m2 for males and ≥95 g/m2 for females) or left atrial enlargement (\>34 mL/m2) or diastolic dysfunction (E/e'≥13 and a mean e' septal and lateral wall \<9 cm/s) were included.
- Then patients were classified according to EF into HFpEF\>50%, HFrEF\<40% and HFmrEF \>40% and \<50%
You may not qualify if:
- Patients with chronic obstructive pulmonary disease history of pulmonary embolism patients with respiratory failure
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- shaimaa Mostafalead
Related Publications (1)
Mostafa S. Assessment of right ventricular systolic function in heart failure with preserved, reduced and mid-range ejection fraction. Indian Heart J. 2019 Sep-Oct;71(5):406-411. doi: 10.1016/j.ihj.2019.11.252. Epub 2019 Nov 20.
PMID: 32035524DERIVED
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- assistant professor of cardiovascular medicicne
Study Record Dates
First Submitted
August 17, 2018
First Posted
August 22, 2018
Study Start
January 1, 2017
Primary Completion
June 1, 2018
Study Completion
July 1, 2018
Last Updated
August 22, 2018
Record last verified: 2018-08