Digestive Properties of Carbohydrate-based Foods
Investigating Digestive Properties of Carbohydrate-based Foods
1 other identifier
interventional
15
1 country
1
Brief Summary
Gastric emptying rate, glycemic response, fermentation, and appetitive response are being assessed after consumption of traditional West African carbohydrate-based foods (pearl millet couscous, pearl millet thick porridge) and Western type carbohydrate-based foods (wheat couscous, white rice).
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable obesity
Started Jun 2018
Shorter than P25 for not_applicable obesity
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 11, 2018
CompletedFirst Submitted
Initial submission to the registry
June 27, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 31, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
July 31, 2018
CompletedFirst Posted
Study publicly available on registry
August 14, 2018
CompletedAugust 22, 2019
August 1, 2019
2 months
June 27, 2018
August 21, 2019
Conditions
Outcome Measures
Primary Outcomes (2)
Gastric emptying rate
Breath test is being performed using 13C-octanoic acid mixed into test meals.
Acute study; 4 hours of measurement after consumption of test food
Glycemic response
Blood glucose is being measured using continuous glucose monitors.
Acute study; 4 hours of measurement after consumption of test food
Secondary Outcomes (2)
Breath hydrogen (fermentability)
Acute study; 4 hours of measurement after consumption of test food
Appetitive response
Acute study; 4 hours of measurement after consumption of test food
Study Arms (5)
Pearl millet couscous - made in Senegal
EXPERIMENTALSteamed pearl millet couscous - commercially produced in Senegal
Pearl millet couscous - made in USA
EXPERIMENTALSteamed pearl millet couscous - pearl millet obtained from Senegal but processed and prepared in USA
Pearl millet thick porridge
EXPERIMENTALThick porridge prepared according to traditional West African methods with pearl millet obtained from Senegal but processed and prepared in USA
Wheat couscous
EXPERIMENTALSteamed wheat couscous - wheat flour processed and prepared in USA
White rice
ACTIVE COMPARATORWhite rice - medium-grain prepared using a rice cooker
Interventions
Pearl millet couscous (made in Senegal) was tested for gastric emptying rate, glycemic response, fermentability, and appetitive response.
Pearl millet couscous (made in USA) was tested for gastric emptying rate, glycemic response, fermentability, and appetitive response.
Pearl millet thick porridge was tested for gastric emptying rate, glycemic response, fermentability, and appetitive response.
Wheat couscous was tested for gastric emptying rate, glycemic response, fermentability, and appetitive response.
White rice was tested as a comparator for gastric emptying rate, glycemic response, fermentability, and appetitive response.
Eligibility Criteria
You may qualify if:
- Normal body mass index (18.5 \< BMI \< 25 kg/m2)
- Normal fasting blood glucose
You may not qualify if:
- Diabetes
- Allergy to millet
- Allergy or sensitivity/intolerance to gluten
- History of gastrointestinal disease
- Pregnant or nursing
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Purdue University
West Lafayette, Indiana, 47907, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- OTHER
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Distinguished Professor of Food Science
Study Record Dates
First Submitted
June 27, 2018
First Posted
August 14, 2018
Study Start
June 11, 2018
Primary Completion
July 31, 2018
Study Completion
July 31, 2018
Last Updated
August 22, 2019
Record last verified: 2019-08
Data Sharing
- IPD Sharing
- Will not share
Individual participant data will not be made available to other researchers.