Evaluation of Visceral Pleural Lumbar Lymphatic Drainage

NCT03628326 | Completed

• 1 other identifier: RNI2016-01
• Study Type: observational
• Target: 44
• Locations: 0 countries
• Sites: N/A

Brief Summary

Anatomic variations of the pulmonary arterial tree can cause technical difficulties during pulmonary lobectomy in general and video-assisted thoracic surgery (VATS). Using CT angiography and 3D reconstruction, the investigators sought to identify anatomic variations of the pulmonary arterial tree and assess their respective frequencies.

Conditions

Pulmonary Artery Stenosis

Keywords

Pulmonary artery; 3D reconstruction; Video-assisted thoracic surgery lobectomy; CT angiography; Anatomic variation

Outcome Measures

Primary Outcomes (1)

• Use CT angiography and 3D reconstruction

  The primary objective of the present study was to use CT angiography and 3D reconstruction to assess the pulmonary arterial tree and its anatomic variations in patients having undergone VATS lobectomy for stage I-II lung cancer. The investigators studied patients having undergone VATS lobectomy for stage I-II lung cancer at the Amiens University Hospital's Department of Thoracic Surgery between October 2012 and March 2014. The investigators performed 3D reconstruction of the pulmonary arterial tree on the CT angiography data set acquired during preoperative work-up. Patients having undergone CT angiography in another hospital, those not having undergone CT angiography of the arterial tree, and those having been operated on more than once for lung cancer were excluded from the study.

  18-month

Study Arms (2)

right lung resection

The investigators sought to identify anatomic variations of the pulmonary arterial tree and assess their respective frequencies.

Other: Pulmonary arterial tree

left lung resection

The investigators sought to identify anatomic variations of the pulmonary arterial tree and assess their respective frequencies.

Other: Pulmonary arterial tree

Interventions

Pulmonary arterial tree OTHER

The investigators performed 3D reconstruction of the pulmonary arterial tree on the CT angiography data set acquired during preoperative work-up.

left lung resection; right lung resection

Eligibility Criteria

• Age: 50 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

The investigators studied patients having undergone VATS lobectomy for stage I-II lung cancer at the Amiens University Hospital's Department of Thoracic Surgery between October 2012 and March 2014. We performed 3D reconstruction of the pulmonary arterial tree on the CT angiography data set acquired during preoperative work-up.

You may qualify if:

• Any major patient aged 18 years and over who has undergone oncological lung lobectomy for non-small-cell lung cancer located in the thoracic surgery department of the University Hospital of Amiens.
• Nosologic criteria and related to acts: The pathology has already been diagnosed or suspected, and the surgical indication has been validated in the Multidisciplinary Thoracic Oncology Concertation Meeting according to national recommendations.
• These patients will be collected in a database already referenced in the register of the establishment of the University Hospital of Amiens under the reference DRCI T38

You may not qualify if:

• Criteria relating to the population:
• Patient under guardianship or curatorship
• Pathology Criteria: Patient with no pulmonary neoplastic disease, patient with locally advanced or metastatic bronchopulmonary cancer
• Criteria relating to the acts: the criteria altering the surgical specimen and thus its anatomical study: patient having had an extemporaneous examination, patient with the antecedents of ipsilateral pulmonary surgery and / or need of decortication

Sponsors & Collaborators

• Centre Hospitalier Universitaire, Amiens: lead

MeSH Terms

Conditions

Stenosis, Pulmonary Artery

Condition Hierarchy (Ancestors)

Arterial Occlusive Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Frederic Marçon, MD

  CHU AMIENS

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 31, 2018
• First Posted: August 14, 2018
• Study Start: April 1, 2016
• Primary Completion: August 1, 2017
• Study Completion: August 1, 2017
• Last Updated: August 14, 2018

Record last verified: 2018-08

Data Sharing

• IPD Sharing: Will not share