Vitamin D Level Among Athletes in Uzbekistan

NCT03623763 | Suspended DMC

• 1 other identifier: #30072018
• Study Type: observational
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

The purpose of the study is to determine vitamin D (VD) levels and upper respiratory tract infections (URTI) morbidity among elite athletes engaged in water sports in Uzbekistan. Serum levels of 25(OH) VD and TNF-α, IFN-γ, IL-4 and IL-6 will be detected by ELISA technique among elite athletes and control population in spring and autumn.

Conditions

Athletes; Respiratory Infection; Cytokines; Vitamin D

Keywords

vitamin D; water sport; IL-4; IL-6; TNF-a; IFN-gamma; athletes; respiratory infection

Outcome Measures

Primary Outcomes (3)

• Vitamin D level in elite athletes

  In this study we expect to determine of serum level of vitamin D in elite athletes of Uzbekistan

  up to 36 months

• Correlation between cytokine status (TNF-α, IFN-γ, IL-4 and IL-6 ) and vitamin D level among elite athletes

  In this study we expect to find association between cytokine status and vitamin D level in elite athletes.

  up to 36 months

• Incidence of upper respiratory infection among elite athletes with vitamin D deficiency/insufficiency/sufficiency

  In this study we expect to find a role of vitamin D in development of upper respiratory infection among elite athletes.

  up to 36 months

Study Arms (3)

Healthy individuals

Individuals without any complaints and chronic diseases

Diagnostic Test: Serologic tests of blood samples

Swimmers

Elite athletes - swimmers to distance of national team of Uzbekistan

Diagnostic Test: Serologic tests of blood samples

Synchronized swimmers

Elite athletes - swimmers of national team of Uzbekistan

Diagnostic Test: Serologic tests of blood samples

Interventions

Serologic tests of blood samples DIAGNOSTIC_TEST

Five milliliters of peripheral venous blood will be (after 8-12 hours of fasting) from each participant and will be collected into Human Tube Serum Gel - C/A for ELISA. All blood samples will be collected in August and January. Serum levels of 25(OH) VD and TNF-α, IFN-γ, IL-4 and IL-6 will be detected by ELISA technique

Healthy individuals; Swimmers; Synchronized swimmers

Eligibility Criteria

• Age: 17 Years - 28 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Probability Sample

Study Population

Healthy individuals Swimmers to distance Synchronized swimmers

You may qualify if:

• Healthy individuals
• Swimmers to distance
• Synchronized swimmers

You may not qualify if:

• chronic infectious and noninfectious diseases
• acute infectious and noninfectious diseases
• history of using VD supplements within six months or drugs usage within three months.

Sponsors & Collaborators

• Research Institute of Epidemiology, Microbiology and Infectious Diseases, Uzbekistan: lead

Related Publications (1)

• Umarov J, Kerimov F, Toychiev A, Davis N, Osipova S. Association of the 25(OH) vitamin D status with upper respiratory tract infections morbidity in water sports elite athletes. J Sports Med Phys Fitness. 2019 Dec;59(12):2058-2065. doi: 10.23736/S0022-4707.19.09834-7. Epub 2019 May 2.

  PMID: 31062952 RESULT

Related Links

• Related Info

MeSH Terms

Conditions

Respiratory Tract Infections

Condition Hierarchy (Ancestors)

Infections; Respiratory Tract Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Year
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Senior researcher

Study Record Dates

• First Submitted: July 29, 2018
• First Posted: August 9, 2018
• Study Start: January 1, 2017
• Primary Completion: January 1, 2026
• Study Completion: April 1, 2026
• Last Updated: March 2, 2023

Record last verified: 2023-03