Effect of Light-Emitting Diode on the Strenght and Resistence Capacities of Cycling Athletes

NCT03225976 | Completed DMC

• 1 other identifier: U1111-1143-7629
• Study Type: interventional
• Target: 48
• Locations: 1 country
• Sites: 1

Brief Summary

Phototherapy is a therapeutic resource of increasing use in the last decade. The photobiomodulatory effects are commonly produced by means of low intensity lasers or LED emitting diodes, and can be used at different wavelengths. These light sources are divergent as to coherence, but produce equivalent tissue effects. The application of laser or LED light is able to induce biochemical changes in tissues, allowing for inhibitory or stimulating effects. These responses are associated to a cascade of cellular reactions, which favor the absorption of enzymes by cytochrome c oxidase, generating physiological responses that lead to decreased production of reactive oxygen species and increased synthesis of adenosine triphosphate (ATP). The application of this therapeutic resource brings ergogenic and protective benefits in muscular performance. The use of LED as a light source is promising because of its low cost, but there are no enough studies that support this use in athletes, with a focus on performance improvement. In addition to the deficiency of the sample, there is also no consensus regarding the use of different wavelengths for LED in the literature, thus opening gaps for the best protocol for the application of this technique. Therefore, a study that evaluates the use of LED in athletes, with different wavelengths, to improve performance is necessary. Hypothesis: It is hypothesized that the LED application is capable of improving athletes performance in terms of increased fatigue resistance, increased strength and power, increased muscle recruitment, and optimized oxygen demand. It is also expected that the results generated in this study can contribute to and increase the resources used by physiotherapists within the clinical-sports field, contributing to the post-training recovery, as well as the more effective physical performance in competitive activities.

Conditions

Athletes

Keywords

Phototherapy; Athletic Performance; Muscle Strength; Fatigue

Outcome Measures

Primary Outcomes (1)

• Strenght Capacities

  N/m

  Twenty minutes

Secondary Outcomes (8)

• Resistence Capacities

  Twenty Minutes

• Muscle recruitment

  Twenty Minutes

• Gas analysis

  Twenty Minutes

• Lactate analysis

  Twenty Minutes

• Creatine Kinase Analysis

  Five Minutes

Study Arms (4)

Infrared LED group (G-I)

EXPERIMENTAL

The Light-Emitting Diode Device with wavelength of 904nm will be applied throughout the quadriceps femoralis extension bilaterally.

Device: Light-Emitting Diode Device

Red LED group (G-V)

EXPERIMENTAL

The Light-Emitting Diode Device with a wavelength of 620nm will be applied throughout the quadriceps femoralis extension bilaterally.

Device: Light-Emitting Diode Device

Sham Group (G-S)

SHAM COMPARATOR

The Sham Light-Emitting Diode Device will be positioned throughout the quadriceps femoral muscle extension, however, there will be no light emission.

Device: Sham Light-Emitting Diode Device

Infrared plus Red LED group (G-IV)

EXPERIMENTAL

The Light-Emitting Diode Device with a wavelength of 620nm plus 904nm will be applied throughout the quadriceps femoralis extension bilaterally.

Device: Light-Emitting Diode Device

Interventions

Light-Emitting Diode Device DEVICE

The therapy will be applied on the second, third and fourth day of collection using a 25x40 cm2 LED blanket, with an equidistant distribution, with total energy per area of 180 J bilaterally on the quadriceps femoris muscle. All LEDs will be calibrated prior to the start of applications in the Laboratory of Photobiophysics of the Faculty of Sciences and Letters of Ribeirão Preto, University of São Paulo, in which the wavelengths will be checked, the angle of radiation, power and power density.

Infrared LED group (G-I); Infrared plus Red LED group (G-IV); Red LED group (G-V)

Sham Light-Emitting Diode Device DEVICE

The Sham Light-Emitting Diode Device will be applied on the second, third and fourth day of collection using a 25x40 cm2 LED blanket, with an equidistant distribution, with total energy per area of 0 J bilaterally on the quadriceps femoris muscle. At the time of application the device will not be activated

Sham Group (G-S)

Eligibility Criteria

• Age: 18 Years - 45 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Cycling practitioners
• Age between 18 and 45 years;
• Male
• VO2MÁX \> 40 ml.kg-1.min-1;
• Absence of musculoskeletal injury in the last six months

You may not qualify if:

• Carriers of Cardiorespiratory Diseases;
• Users of anti-inflammatory and analgesic drugs
• Users of Alcohol and illicit drugs

Sponsors & Collaborators

• University of Sao Paulo: lead

Study Sites (1)

University of São Paulo

Ribeirão Preto, São Paulo, Brazil

Location

Related Publications (2)

• Ferraresi C, Huang YY, Hamblin MR. Photobiomodulation in human muscle tissue: an advantage in sports performance? J Biophotonics. 2016 Dec;9(11-12):1273-1299. doi: 10.1002/jbio.201600176. Epub 2016 Nov 22.

  PMID: 27874264 RESULT

• de Carvalho G, Gobbi A, Gobbi RB, Alfredo DMN, do Carmo Furquim TH, Barbosa RI, Papoti M, de Jesus Guirro RR. Photobiomodulation by light emitting diode applied sequentially does not alter performance in cycling athletes. Lasers Med Sci. 2020 Oct;35(8):1769-1779. doi: 10.1007/s10103-020-02973-9. Epub 2020 Feb 20.

  PMID: 32078062 DERIVED

Related Links

• Page intended to research scientific articles published in journals

MeSH Terms

Conditions

Fatigue

Condition Hierarchy (Ancestors)

Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Rinaldo RJ Roberto de Jesus Guirro, Dr

  University of Sao Paulo

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor Doctoral

Model Details: Athletes will be randomized allocated the following groups: * Infrared LED group (G-I; n = 12) * Red LED group (G-V; n = 12) * Infrared plus Red LED group (G-IV; n = 12) * Sham Group (G-S; n = 12)

Study Record Dates

• First Submitted: July 19, 2017
• First Posted: July 21, 2017
• Study Start: January 25, 2018
• Primary Completion: December 25, 2018
• Study Completion: March 12, 2019
• Last Updated: April 29, 2021

Record last verified: 2021-04

Data Sharing

• IPD Sharing: Will not share

Locations

BR (1)