NCT03621566

Brief Summary

This study evaluates different factors that determine the treatment choice and treatment compliance in patients with central sleep apnea. All patients will receive routine care (registry).

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,500

participants targeted

Target at P75+ for all trials

Timeline
26mo left

Started Jun 2018

Longer than P75 for all trials

Geographic Reach
1 country

14 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress79%
Jun 2018Jun 2028

Study Start

First participant enrolled

June 25, 2018

Completed
10 days until next milestone

First Submitted

Initial submission to the registry

July 5, 2018

Completed
1 month until next milestone

First Posted

Study publicly available on registry

August 8, 2018

Completed
9.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 25, 2028

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 25, 2028

Last Updated

July 3, 2024

Status Verified

July 1, 2024

Enrollment Period

10 years

First QC Date

July 5, 2018

Last Update Submit

July 2, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Treatment choice

    Proportion of patients treated with the different treatment modalities

    5 years

Secondary Outcomes (5)

  • Factors determining treatment choice

    5 years

  • Treatment compliance

    5 years

  • Short Form 36 Health Survey

    5 years

  • Pitssburgh Sleep Quality index

    5 years

  • Mortality

    5 years

Study Arms (1)

Central Sleep Apnea

Subjects with an apnea/hypopnea index ≥ 15/h of sleep and proportion of non-obstructive events \> 50%, derived from polysomnography (diagnostic or during positive airway pressure treatment)

Other: No intervention

Interventions

Routine care (registry)

Central Sleep Apnea

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Subjects with an apnea/hypopnea index ≥ 15/h of sleep and proportion of non-obstructive events \> 50%, derived from polysomnography (diagnostic or during positive airway pressure treatment)

You may qualify if:

  • Age ≥ 18 years old
  • An apnea/hypopnea index ≥ 15/h of sleep and proportion of non-obstructive events \> 50%, derived from polysomnography (diagnostic or during (PAP) treatment)
  • Written informed consent provided

You may not qualify if:

  • \- Patients with mental disability making it impossible to understand the study protocol

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (14)

OLV Ziekenhuis

Aalst, 9300, Belgium

RECRUITING

ZNA Middelheim

Antwerp, 2020, Belgium

RECRUITING

UZA

Antwerp, 2650, Belgium

RECRUITING

AZ Sint-Jan

Bruges, 8000, Belgium

RECRUITING

CHU Saint-Pierre

Brussels, 1000, Belgium

RECRUITING

Ghent University Hospital

Ghent, 9000, Belgium

RECRUITING

Jessa Ziekenhuis

Hasselt, 3500, Belgium

RECRUITING

AZ Groeninge

Kortrijk, 8500, Belgium

RECRUITING

CH Jolimont

La Louvière, 7100, Belgium

RECRUITING

UZ Leuven

Leuven, 3000, Belgium

RECRUITING

CHR de la Citadelle

Liège, 4000, Belgium

RECRUITING

CHU UCL Namur

Namur, 5530, Belgium

RECRUITING

AZ Glorieux

Ronse, 9600, Belgium

RECRUITING

AZ Turnhout

Turnhout, 2300, Belgium

RECRUITING

MeSH Terms

Conditions

Sleep Apnea, Central

Condition Hierarchy (Ancestors)

Sleep Apnea SyndromesApneaRespiration DisordersRespiratory Tract DiseasesSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System Diseases

Study Officials

  • Dries Testelmans, MD, PhD

    UZ Leuven

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Dries Testelmans, MD, PhD

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
5 Years
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 5, 2018

First Posted

August 8, 2018

Study Start

June 25, 2018

Primary Completion (Estimated)

June 25, 2028

Study Completion (Estimated)

June 25, 2028

Last Updated

July 3, 2024

Record last verified: 2024-07

Data Sharing

IPD Sharing
Will not share

Locations