NCT01939535

Brief Summary

The purpose of the study is to evaluate the value of MRI in preoperative stratification of endometriosis patients needing surgical approach by gynaecologists only or multidisciplinary approach by gynaecologists, urologists or/and abdominal surgeons.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
120

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Sep 2013

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 27, 2013

Completed
2 months until next milestone

Study Start

First participant enrolled

September 1, 2013

Completed
10 days until next milestone

First Posted

Study publicly available on registry

September 11, 2013

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2016

Completed
1.3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 7, 2017

Completed
Last Updated

December 8, 2017

Status Verified

November 1, 2016

Enrollment Period

3 years

First QC Date

June 27, 2013

Last Update Submit

December 7, 2017

Conditions

Keywords

EndometriosisMagnetic resonance imaging

Outcome Measures

Primary Outcomes (1)

  • Odds of changed surgical approach in deep endometriosis based on preoperative MRI findings.

    All endometriosis lesions found on MRI will be checked during laparoscopy in order to determine how the MRI findings might have changed the decision to do a surgical approach by gynaecologists only or multidisciplinary approach by gynaecologists, urologists or/and abdominal surgeons, and this compared to the conventional preoperative imaging approach (double contrast barium enema, intravenous urography and ultrasound.

    All the imaging findings will be checked during a laparoscopy the latest 80 weeks after the imaging examinations.

Study Arms (1)

Women with endometriosis

Women with endometriosis with the intention of surgery - no intervention

Other: No intervention

Interventions

Evaluation of an imaging technique ic MRI

Women with endometriosis

Eligibility Criteria

Sexfemale
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Women with endometriosis in a tertiary referral centre

You may qualify if:

  • Women with strong suspicion of deep infiltrating endometriosis, with already planned surgery

You may not qualify if:

  • Contra-indications for MRI; claustrophobic patients; patients in bad condition; pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospitals KULeuven

Leuven, 3000, Belgium

Location

MeSH Terms

Conditions

Endometriosis

Condition Hierarchy (Ancestors)

Genital Diseases, FemaleFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesGenital Diseases

Study Officials

  • Didier Bielen, PhD

    University Hospitals KULeuven

    PRINCIPAL INVESTIGATOR
  • Elvier Mussen, MD

    University Hospitals KULeuven

    PRINCIPAL INVESTIGATOR
  • Carla Tomassetti, MD

    University Hospitals KULeuven

    PRINCIPAL INVESTIGATOR
  • Christel Meuleman, PhD

    University Hospitals KULeuven

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 27, 2013

First Posted

September 11, 2013

Study Start

September 1, 2013

Primary Completion

September 1, 2016

Study Completion

December 7, 2017

Last Updated

December 8, 2017

Record last verified: 2016-11

Locations