Home-based Exercise in Chronic Kidney Disease

NCT03621176 | Completed

• 1 other identifier: HBCKD
• Study Type: interventional
• Target: 57
• Locations: 1 country
• Sites: 1

Brief Summary

A home-based exercise program will be implemented in three different groups of participants: advanced chronic kidney disease, end-stage renal disease in substitutive treatment hemodialysis or peritoneal dialysis. Participants will be evaluated before the program, after 3 months and after 6 months from the starting of the program. During the first 3 months the researcher will phone them weekly to reinforce the exercise habit, and during the last three months, there will be no reinforcement. Assessment will include strength, functional capacity, health-related quality of life and depressive symptoms.

Conditions

Chronic Kidney Disease; End-stage Renal Disease

Keywords

Exercise; Health-related quality of life; Physical function; Hemodialysis; Peritoneal dialysis

Outcome Measures

Primary Outcomes (1)

• Change from baseline sit to stand 10 test at 12 and 24 weeks

  Sit to stand to sit test 10, time to perform 10 repetitions

  Baseline,1 week, non-dialysis day baseline,12 weeks, 24 weeks

Secondary Outcomes (13)

• Change from baseline Six-minute walking test at 12 and 24 weeks

  Baseline,1 week, non-dialysis day baseline,12 weeks, 24 weeks

• Change from baseline STS-60 at 12 and 24 weeks

  Baseline,1 week, non-dialysis day baseline,12 weeks, 24 weeks

• Change from baseline OLHR at 12 and 24 weeks

  Baseline,1 week, non-dialysis day baseline,12 weeks, 24 weeks

• Change from baseline Handgrip strength (dynamometry) at 12 and 24 weeks

  Baseline,1 week, non-dialysis day baseline,12 weeks, 24 weeks

• Change from baseline SPPB at 12 and 24 weeks

  Baseline,1 week, non-dialysis day baseline,12 weeks, 24 weeks

Study Arms (1)

Home-based exercise

EXPERIMENTAL

Home-based intervention in the advanced chronic kidney disease group, hemodialysis or peritoneal dialysis group

Other: Home-based exercise

Interventions

Home-based exercise OTHER

A booklet with detailed information will be provided, and the exercises will be previously reviewed with every patient by the researcher. Participants will be encouraged to perform at least 3 sessions per week and monitor their heart rate. They will be instructed that the exercises should be perceived as 'somewhat hard' from a rate of perceived exertion. Adaptations to increase the intensity of the exercises will be provided so that participants can progress in exercise intensity

Home-based exercise

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• At least 3 months in hemodialysis treatment
• Clinically stable

You may not qualify if:

• Recent cardiac events (less than 3 months)
• Unable to exercise

Sponsors & Collaborators

• Cardenal Herrera University: lead
• Consorci Sanitari de Terrassa. Hospital de Terrassa: collaborator

Study Sites (1)

Hospital de Terrassa

Terrassa, Barcelona, 08227, Spain

Location

Related Publications (2)

• Esteve Simo V, Junque Jimenez A, Moreno Guzman F, Carneiro Oliveira J, Fulquet Nicolas M, Pou Potau M, Saurina Sole A, Duarte Gallego V, Tapia Gonzalez I, Ramirez de Arellano M. Benefits of a low intensity exercise programme during haemodialysis sessions in elderly patients. Nefrologia. 2015;35(4):385-94. doi: 10.1016/j.nefro.2015.03.006. Epub 2015 Jul 21. English, Spanish.

  PMID: 26306966 BACKGROUND

• Segura-Orti E, Martinez-Olmos FJ. Test-retest reliability and minimal detectable change scores for sit-to-stand-to-sit tests, the six-minute walk test, the one-leg heel-rise test, and handgrip strength in people undergoing hemodialysis. Phys Ther. 2011 Aug;91(8):1244-52. doi: 10.2522/ptj.20100141. Epub 2011 Jun 30.

  PMID: 21719637 BACKGROUND

MeSH Terms

Conditions

Renal Insufficiency, Chronic; Kidney Failure, Chronic; Motor Activity

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Behavior

Study Officials

• Vicent Esteve-Simó, PhD

  Hospital de Terrassa

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Model Details: All participants will undertake the exercise intervention. We will compare effects of the intervention between different cohorts included (advanced chronic kidney disease, end-stage renal disease hemodialysis o peritoneal dialysis)

Study Record Dates

• First Submitted: July 23, 2018
• First Posted: August 8, 2018
• Study Start: August 1, 2018
• Primary Completion: January 31, 2019
• Study Completion: February 14, 2019
• Last Updated: February 27, 2019

Record last verified: 2019-02

Data Sharing

• IPD Sharing: Will not share

Locations

ES (1)