Fatigability and Physical Performance: Effects of Resistance Training Variables Manipulation

NCT03619070 | Unknown DMC

• 1 other identifier: 85052218.0.0000.5154
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

This study evaluate whether resistance training variables modulate the fatigability (power-duration relationship) and physical performance in adults and older adults

Conditions

Aging

Keywords

Fatigability; Postmenopausal Woman; Resistance training; Physical performance; Older adults

Outcome Measures

Primary Outcomes (1)

• Fatigability

  The fatigability will be evaluate by 60 maximum voluntary isometric contractions (3 s contraction, 2 s rest) in knee extensors at 70 degree.

  Changes in fatigability measure (e.g. baseline and after 12 weeks of intervention)

Secondary Outcomes (1)

• Physical Performance

  Changes in physical performance measure (e.g. baseline and after 12 weeks of intervention)

Other Outcomes (2)

• Body composition

  Changes in body composition (e.g. baseline and after 12 weeks of intervention)

• Muscle strength

  Changes in muscle strength (e.g. baseline and after 12 weeks of intervention)

Study Arms (4)

Lower load resistance training (LL)

EXPERIMENTAL

In the LL group, postmenopausal women will perform the resistance training with moderate volume (i.e. three sets per exercise performed until or close to failure) and low load (i.e. 30% of 1RM)

Other: Resistance training, LL

Higher load resistance training (HL)

EXPERIMENTAL

In the HL group, postmenopausal women will perform the resistance training with moderate volume (i.e. three sets per exercise performed until or close to failure) and high load (i.e. 80% of 1RM)

Other: Resistance training, HL

Higher volume resistance training (HVHL)

EXPERIMENTAL

In the HVHL group, postmenopausal women will perform the resistance training with high volume (i.e. six sets per exercise performed until or close to failure) and high load (i.e. 80% of 1RM)

Other: Resistance training, HVHL

Control group, (CG)

OTHER

In CG, the postmenopausal women group will not perform exercise

Other: Control group, CG

Interventions

Resistance training, LL OTHER

In LL, the postmenopausal women will be submitted to 12 weeks of Resistance training with moderate volume (i.e. three sets per exercise) and low load (i.e. 30% of one repetition maximum)

Lower load resistance training (LL)

Resistance training, HL OTHER

In HL, the postmenopausal women will be submitted to 12 weeks of Resistance training with moderate volume (i.e. three sets per exercise) and high load (i.e. 80% of one repetition maximum)

Higher load resistance training (HL)

Resistance training, HVHL OTHER

In HVHL, the postmenopausal women will be submitted to 12 weeks of Resistance training with high volume (i.e. six sets per exercise) and hig load (i.e. 80% of one maximum repetition)

Higher volume resistance training (HVHL)

Control group, CG OTHER

The CG groups do not will performed the exercise.

Control group, (CG)

Eligibility Criteria

• Age: 50 Years+
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Postmenopausal women (\>12 months amenorrhea) with age above or equal 50 years old.
• No hormone therapy or phytoestrogens

You may not qualify if:

• No-drinker alcohol (no alcohol intake whatsoever in their diet);
• Non- smokers;
• Hypertensive with uncontrolled blood pressure values;
• Diabetic with uncontrolled glycemia;
• Presence of arthropathies;
• Presence of myopathies;
• Skeletal musculotendinous disorder.

Sponsors & Collaborators

• Universidade Federal do Triangulo Mineiro: lead

Study Sites (1)

Post-degree program in physical education

Uberaba, MG - Minas Gerais, 38061-500, Brazil

RECRUITING

Related Publications (24)

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• Lera Orsatti F, Nahas EA, Maesta N, Nahas Neto J, Lera Orsatti C, Vannucchi Portari G, Burini RC. Effects of resistance training frequency on body composition and metabolics and inflammatory markers in overweight postmenopausal women. J Sports Med Phys Fitness. 2014 Jun;54(3):317-25.

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• Nunes PR, Barcelos LC, Oliveira AA, Furlanetto Junior R, Martins FM, Orsatti CL, Resende EA, Orsatti FL. Effect of resistance training on muscular strength and indicators of abdominal adiposity, metabolic risk, and inflammation in postmenopausal women: controlled and randomized clinical trial of efficacy of training volume. Age (Dordr). 2016 Apr;38(2):40. doi: 10.1007/s11357-016-9901-6. Epub 2016 Mar 17.

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• Nunes PRP, Barcelos LC, Oliveira AA, Furlanetto R Jr, Martins FM, Resende EAMR, Orsatti FL. Muscular Strength Adaptations and Hormonal Responses After Two Different Multiple-Set Protocols of Resistance Training in Postmenopausal Women. J Strength Cond Res. 2019 May;33(5):1276-1285. doi: 10.1519/JSC.0000000000001788.

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• Nunes PRP, Oliveira AA, Martins FM, Souza AP, Orsatti FL. Effect of resistance training volume on walking speed performance in postmenopausal women: A randomized controlled trial. Exp Gerontol. 2017 Oct 15;97:80-88. doi: 10.1016/j.exger.2017.08.011. Epub 2017 Aug 10.

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• Orsatti FL, Maesta N, de Oliveira EP, Nahas Neto J, Burini RC, Nunes PRP, Souza AP, Martins FM, Nahas EP. Adding Soy Protein to Milk Enhances the Effect of Resistance Training on Muscle Strength in Postmenopausal Women. J Diet Suppl. 2018 Mar 4;15(2):140-152. doi: 10.1080/19390211.2017.1330794. Epub 2017 Jun 12.

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• Orsatti FL, Nahas EA, Maesta N, Nahas-Neto J, Burini RC. Plasma hormones, muscle mass and strength in resistance-trained postmenopausal women. Maturitas. 2008 Apr 20;59(4):394-404. doi: 10.1016/j.maturitas.2008.04.002. Epub 2008 May 21.

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• Orsatti FL, Nahas EA, Orsatti CL, de Oliveira EP, Nahas-Neto J, da Mota GR, Burini RC. Muscle mass gain after resistance training is inversely correlated with trunk adiposity gain in postmenopausal women. J Strength Cond Res. 2012 Aug;26(8):2130-9. doi: 10.1519/JSC.0b013e318239f837.

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MeSH Terms

Interventions

Resistance Training; Control Groups

Intervention Hierarchy (Ancestors)

Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena; Epidemiologic Research Design; Epidemiologic Methods; Investigative Techniques; Research Design; Methods

Study Officials

• Fabio L Orsatti, PhD

  Federal University of Triangulo Mineiro

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Fabio L Orsatti, PhD

CONTACT

+55343700-6634; fabiorsatti@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: August 1, 2018
• First Posted: August 7, 2018
• Study Start: May 20, 2018
• Primary Completion: September 30, 2018
• Study Completion: November 15, 2018
• Last Updated: August 8, 2018

Record last verified: 2018-08

Data Sharing

• IPD Sharing: Will not share

Locations

BR (1)