NCT03206580

Brief Summary

Life expectancy and elderly population are increasing. Health professionals try to provide longevity with good quality of life for this population, through the functional independence maintenance. In this context, physical exercise has an important role, specially the strength training. The ability to produce muscle strength is positively associated with the functionality and independence of older people. Different types of strength training can lead to different neuromuscular and functional gains. These types of interventions can help health professionals to determine characteristics of training for the elderly, aiming the maintenance of their functional independence. Thus, the purpose of this study is to determine the effects of a concentric strength training versus a concentric-eccentric strength training for knee flexors and extensors on structural, neuromuscular and functional parameters in older people, as well as to investigate the effect of a detraining period. Additionally, the investigators will try to identify which structural and neuromuscular parameters of lower limbs are better related to the functionality.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
11

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2016

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 15, 2016

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

June 22, 2017

Completed
10 days until next milestone

First Posted

Study publicly available on registry

July 2, 2017

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2018

Completed
Last Updated

June 10, 2024

Status Verified

June 1, 2024

Enrollment Period

2.2 years

First QC Date

June 22, 2017

Last Update Submit

June 7, 2024

Conditions

Keywords

agingstrength trainingfunctionality

Outcome Measures

Primary Outcomes (16)

  • Pennation angle of rectus femoris, vastus lateralis and biceps femoris, bilaterally.

    Pennation angle at rest

    First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining

  • Thickness of rectus femoris, vastus lateralis and biceps femoris, bilaterally.

    Muscle thickness at rest

    First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining

  • Fascicle length of rectus femoris, vastus lateralis and biceps femoris, bilaterally.

    Fascicle length at rest

    First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining

  • Echo intensity of rectus femoris, vastus lateralis and biceps femoris, bilaterally.

    Echo intensity determined from a gray scale analysis of the muscles at rest

    First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining

  • Countermovement vertical jump

    Maximal vertical height in the countermovement jump

    First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining

  • Timed-up-&-go

    Time to rise from a chair, walk 3 meters, turn, walk back and sit again

    First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining

  • Unipodal static balance

    Range in anterior-posterior and medio-lateral center of pressure movement during unipodal evaluation during 30 seconds

    First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining

  • Gait speed

    Gait speed for walking 10 meters at self-selected speed

    First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining

  • Stair ascent and descent time

    Time to stair ascent and descent stairs

    First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining

  • 6-minutes walking test

    The distance that the subjects can walk during 6 minutes

    First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining

  • Sit-to-stand

    Maximal number of repetitions during 30 seconds

    First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining

  • Power of knee extensors and knee flexors

    Power during maximal concentric and eccentric contractions

    First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining

  • Rate of torque production of knee extensors and knee flexors

    Rate of torque production during maximal isometric contractions

    First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining

  • Strength of knee extensors and knee flexors

    Maximal isometric strength

    First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining

  • Strength of knee extensors and knee flexors

    Maximal concentric strength

    First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining

  • Strength of knee extensors and knee flexors

    Maximal eccentric strength

    First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining

Study Arms (2)

Concentric training

EXPERIMENTAL

Concentric training

Other: Concentric training

Concentric-eccentric training

EXPERIMENTAL

Concentric-eccentric training

Other: Concentric-Eccentric training

Interventions

Subjects will be submitted to 8 weeks (16 sessions) of a concentric training for knee flexors and knee extensors. This training will be performed in an isokinetic dynamometer at 70% of the subject's maximal voluntary isometric contraction.

Concentric training

Subjects will be submitted to 8 weeks (16 sessions) of a concentric-eccentric training for knee flexors and knee extensors. This training will be performed in an isokinetic dynamometer at 70% of the subject's maximal voluntary isometric contraction.

Concentric-eccentric training

Eligibility Criteria

Age65 Years - 85 Years
Sexmale
Healthy VolunteersYes
Age GroupsOlder Adult (65+)

You may qualify if:

  • Male;
  • years of age or more;
  • able to walk independently;
  • not engaged in regular physical exercise.

You may not qualify if:

  • Auditory, vestibular, visual and/or neuromusculoskeletal impairments that could influence the tests and the training;
  • severe cognitive impairment;
  • lower limb surgery;
  • osteoporosis;
  • lower limb pain.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Exercise Research Laboratory, School of Physical Education, Federal University of Rio Grande do Sul

Porto Alegre, Rio Grande do Sul, 90690-200, Brazil

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

June 22, 2017

First Posted

July 2, 2017

Study Start

October 15, 2016

Primary Completion

December 31, 2018

Study Completion

December 31, 2018

Last Updated

June 10, 2024

Record last verified: 2024-06

Locations