Study Stopped
Due tot he Pandemic we decided to terminate this project.
Effects of Hookah (Waterpipe) Smoking on Blood Vessel Function
Effects of Hookah Smoking on Vascular Regulation: Novel Insight Into Endothelial Function
Sponsor study identifier
interventional
58
1 country
1
Study Start
January 1, 2015
Actual (reported)Primary Completion
March 2020
Actual (reported)Study Completion
March 2020
Actual (reported)The purpose of this study is to assess the acute effects of Hookah (waterpipe) smoking on blood vessel function. Hookah smoking has been shown to immediately increase blood pressure and heart rate which could result in damage in the inner lining of the body's blood vessels.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
March 2020
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
January 1, 2015
Actual (reported)January 13, 2015
Actual (reported)August 6, 2018
Actual (reported)March 2020
Actual (reported)March 2020
Actual (reported)Brachial artery flow-mediated dilation
change from baseline to immediately after smoking
Reactive hyperemia peripheral arterial tonometry
change from baseline to immediately after smoking
Pulse wave velocity
change from baseline to immediately after smoking
aortic pressure waveform
change from baseline to immediately after smoking
Healthy habitual Hookah smokers will undergo brachial artery flow mediated dilation, reactive hyperemia peripheral arterial tonometry or pulse tonometry before and after Hookah smoking.
ad lib hookah smoking for 30 minutes in a controlled laboratory environment.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Cedars-Sinai Medical Center
Los Angeles, California, 90048, United States
Rezk-Hanna M, Mosenifar Z, Benowitz NL, Rader F, Rashid M, Davoren K, Moy NB, Doering L, Robbins W, Sarna L, Li N, Chang LC, Elashoff RM, Victor RG. High Carbon Monoxide Levels from Charcoal Combustion Mask Acute Endothelial Dysfunction Induced by Hookah (Waterpipe) Smoking in Young Adults. Circulation. 2019 May 7;139(19):2215-2224. doi: 10.1161/CIRCULATIONAHA.118.037375.
Florian Rader, MD
Cedars-Sinai Medical Center
First Submitted
January 13, 2015
First Posted
August 6, 2018
Study Start
January 1, 2015
Actual (reported)Primary Completion
March 2020
Actual (reported)Effect of Concurrent Hookah and Alcohol Consumption on Smoking Topography and Toxicant Exposure
Contact the study team to confirm eligibility.
Study Completion
March 2020
Actual (reported)Last Updated
February 4, 2021
Record last verified: 2021-02
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: