Effects of Simultaneous or Sequential Combination of Physical and Cognitive Training

NCT03614182 | Completed

• 1 other identifier: 201702091B0
• Study Type: interventional
• Target: 70
• Locations: 1 country
• Sites: 1

Brief Summary

The objective of this study is to investigate psychometric properties of dual-task walking assessments and compare effects of simultaneous or sequential combination of physical and cognitive training on dual-task walking and cognitive performance for community-dwelling healthy older adults.

Conditions

Healthy Older Adults

Outcome Measures

Primary Outcomes (2)

• gait speed

  Participants will walk 10m at their preferred speed and at fast speed. A 12-meter walkway will be used for walking testing. In order to allow the subjects to have enough distance to accelerate and decelerate, only the time taken to walk the middle 10 meters will be recorded by a stopwatch. The primary gait parameter is gait speed (cm/s) under dual-task walking conditions using the 10 Meter Walking Test,

  5 minutes

• composite score

  A composite score for cognitive-task performance will be calculated by dividing the accuracy (% correct responses) with the reaction time of correct answers (milliseconds), which accounts for speed-accuracy trade-offs in the overall dual-task effect.

  10 minutes

Secondary Outcomes (9)

• Berg Balance Scale (BBS).

  5-10 minutes

• Mini-Balance Evaluation Systems Test (Mini-BESTest).

  10 minutes

• Timed Up and Go Test (TUG).

  2 minutes

• Functional Gait Assessment (FGA).

  10 minutes

• Physical Activity Scale for the Elderly (PASE).

  5 minutes

Study Arms (3)

physical training concurrent with cognitive training

EXPERIMENTAL

The physical training concurrent with cognitive training group (the P+C group) will receive training at progressively increasing task difficulty 3 times a week for 12 weeks and followed by another 12 weeks without exercise (follow-up).

Device: physical training concurrent with cognitive training

physical training followed by cognitive training

ACTIVE COMPARATOR

The physical training followed by cognitive training will receive training at progressively increasing task difficulty 3 times a week for 12 weeks and followed by another 12 weeks without exercise (follow-up).

Device: physical training followed by cognitive training

physical training without cognitive training

ACTIVE COMPARATOR

The physical training without cognitive training group will receive training at progressively increasing task difficulty 3 times a week for 12 weeks and followed by another 12 weeks without exercise (follow-up).

Device: physical training without cognitive training

Interventions

physical training concurrent with cognitive training DEVICE

The P+C group will undertake standing balance, stepping, and treadmill walking training while concurrently perform cognitive tasks.

Also known as: P+C

physical training concurrent with cognitive training

physical training followed by cognitive training DEVICE

The P-then-C group will train the same set of standing balance, stepping, and treadmill walking activities as the P+C group while followed by cognitive training later.

Also known as: P-then-C

physical training followed by cognitive training

physical training without cognitive training DEVICE

The P group will only train the same set of standing balance, stepping, and treadmill walking activities as the other two groups.

Also known as: P

physical training without cognitive training

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)

You may qualify if:

• age more than 65 years old
• able to walk 10 m;
• no severe vision, hearing, cognition, and language problems.

You may not qualify if:

• neurological or musculoskeletal diagnosis that affects walking
• unable standing for at least 2 minutes,
• MMSE score \<24 or severe uncorrected visual deficits
• moderate to severe high blood pressure (systolic pressure ≧ 160mmHg and diastolic blood pressure ≧ 100mmHg )

Sponsors & Collaborators

• Chang Gung University: lead

Study Sites (1)

Chang Gung University

Taoyuan District, 333, Taiwan

Location

MeSH Terms

Interventions

Cognitive Training; Precision Medicine

Intervention Hierarchy (Ancestors)

Neurological Rehabilitation; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Health Services; Health Care Facilities Workforce and Services

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associated Professor

Study Record Dates

• First Submitted: July 31, 2018
• First Posted: August 3, 2018
• Study Start: August 6, 2018
• Primary Completion: May 31, 2021
• Study Completion: May 31, 2021
• Last Updated: July 28, 2021

Record last verified: 2021-07

Data Sharing

• IPD Sharing: Will not share

Locations

TW (1)