Effect of Different Form of Upper Limb Muscles Training on Dyspnea in COPD

NCT03611036 | Completed

• 1 other identifier: REHABSUP (29BRC18.0070)
• Study Type: interventional
• Target: 280
• Locations: 1 country
• Sites: 2

Brief Summary

Evaluate the effect of upper limbs strength training versus the effect of upper limbs endurance training, on dyspnea, in patients with COPD during a pulmonary rehabilitation program.

Conditions

COPD

Outcome Measures

Primary Outcomes (1)

• Compare the effect of upper limbs strength training versus the effect of upper limb endurance training on dyspnea in patients with COPD during a pulmonary rehabilitation program.

  Measurement of dyspnea using the London Chest Daily Activity Living (LCADL) questionnaire. This 15-item, self-administered questionnaire allows an evaluation of dyspnea in patients with COPD during daily activities divided into four components: self-care, domestic, physical, and leisure. Patients could score from 0: "I would not do anyway" to 5: "I need someone else to do this". LCADL score is calculated by aggregating the points assigned to each question, with a higher score representing maximal disability.

  Change from inclusion at 4 week

Secondary Outcomes (6)

• Compare dyspnea in daily life between the 2 groups

  At inclusion and week 4

• Compare dyspnea in daily life between the 2 groups

  At inclusion and week 4

• Measuring upper limb endurance

  At inclusion and week 4

• Compare dyspnea at the end of a functional test using the upper limbs

  At inclusion and week 4

• Compare upper limbs muscle fatigue at the end of a functional test using the upper limbs

  At inclusion and week 4

Study Arms (2)

Strength

EXPERIMENTAL

Patients will follow the pulmonary rehabilitation program associated with upper limbs strength training for a duration of 4 weeks

Other: Strength training

Endurance

ACTIVE COMPARATOR

Patients will follow the pulmonary rehabilitation program associated with upper limbs endurance training for a duration of 4 weeks

Other: Endurance training

Interventions

Strength training OTHER

Upper limbs Strength training; done with dumbbells whose weight corresponds to 60-80% of the maximal voluntary force in abduction measured initially, during 4 weeks

Strength

Endurance training OTHER

Upper limbs Endurance training of the ; done with dumbbells whose weight corresponds to 30% of the maximum voluntary force in abduction measured initially, during 4 weeks

Endurance

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patient with stage 2 to 4 (A to D) COPD admitted to a pulmonary rehabilitation program (4 weeks)
• Patient aged 18 or over
• Patient able to consent and having signed a consent form

You may not qualify if:

• Patient with pain, osteoarthritis or shoulder surgery
• Patient with a history of Pneumonectomy, lobectomy less than 6 months old
• Refusal of participation
• Patient with an inability to complete a pulmonary rehabilitation program in totality
• Pregnant or breast-feeding women
• Patient under tutorship or curatorship

Sponsors & Collaborators

• University Hospital, Brest: lead

Study Sites (2)

CHRU de Brest

Brest, France

Location

CH Pays de Morlaix

Morlaix, 29672, France

Location

Related Publications (2)

• Beaumont M, Peran L, Berriet AC, Ber CL, Courtois-Communier E, Couturaud F. Effect of different forms of upper limb muscle training on dyspnea in chronic obstructive pulmonary disease: a randomised controlled trial. Ann Phys Rehabil Med. 2025 Oct;68(7):102021. doi: 10.1016/j.rehab.2025.102021. Epub 2025 Sep 17.

  PMID: 40966966 DERIVED

• Beaumont M, Peran L, Berriet AC, Le Ber C, Le Mevel P, Courtois-Communier E, Couturaud F. Effect of different form of upper limb muscles training on dyspnea in chronic obstructive pulmonary disease: A study protocol. Medicine (Baltimore). 2020 Sep 18;99(38):e22131. doi: 10.1097/MD.0000000000022131.

  PMID: 32957334 DERIVED

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Interventions

Resistance Training; Endurance Training

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Marc BEAUMONT, PhD

  CH des pays de Morlaix

  PRINCIPAL INVESTIGATOR

• Francis COUTURAUD, MD, PhD

  CHRU de Brest

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: This is a multicenter, prospective, randomized, open-label study.

Study Record Dates

• First Submitted: July 16, 2018
• First Posted: August 2, 2018
• Study Start: November 21, 2018
• Primary Completion: February 6, 2023
• Study Completion: February 6, 2023
• Last Updated: January 24, 2025

Record last verified: 2025-01

Locations

FR (2)