NCT03584503

Brief Summary

Suction Above Cuff Endotracheal Tube (SACETT) has a dorsal port above the cuff designed to allow continuous or intermittent suctioning of secretions from the subglottic space. Thus, it facilitates suctioning of excessive secretions around the mouth and the cuff. In this study, we aimed to investigate the effect of the use of SACETT on laryngospasm and postoperative complications in rhinoplasty operations. This randomized controlled clinical trial was conducted in 132 patients undergoing rhinoplasty. The investigators believe that the use of SACETT in rhinoplasty operations reduces the incidences of laryngospasm, emergence agitation, sore throat, swallowing difficulty, and PONV when compared with classic endotracheal tube.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
132

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jun 2018

Shorter than P25 for not_applicable

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2018

Completed
18 days until next milestone

First Submitted

Initial submission to the registry

June 19, 2018

Completed
23 days until next milestone

First Posted

Study publicly available on registry

July 12, 2018

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 30, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 30, 2018

Completed
Last Updated

December 4, 2018

Status Verified

December 1, 2018

Enrollment Period

5 months

First QC Date

June 19, 2018

Last Update Submit

December 1, 2018

Conditions

Keywords

general anesthesialaryngospasmpostoperative complicationsrhinoplastySuction Above Cuff Endotracheal Tube

Outcome Measures

Primary Outcomes (1)

  • Incidence of laryngospasm

    While the presence of findings such as apnea (an apneic event was counted by either documentation of apnea by nursing notes through visual observation or documented pauses ≥15 s), desaturation (peripheral oxygen saturation \<85%) and inspiratory stridor (Stridor is a harsh, vibratory sound of variable pitch caused by partial obstruction of the respiratory passages that results in turbulent airflow through the airway) after extubation was considered as laryngospasm.

    1 mounth

Secondary Outcomes (1)

  • emergence agitation

    1 mounth

Study Arms (2)

Group SA

ACTIVE COMPARATOR

Group SA intubated with Suction Above Cuff Endotracheal Tube

Other: Suction Above Cuff Endotracheal Tube

Group C

NO INTERVENTION

Group C intubated with classic endotracheal tube

Interventions

Suction Above Cuff Endotracheal Tube (SACETT) has a dorsal port above the cuff designed to allow continuous or intermittent suctioning of secretions from the subglottic space

Group SA

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients who will undergo rhinoplasty surgery,
  • American Society of Anesthesiologists (ASA) I-II patients,
  • Aged 18-65 years

You may not qualify if:

  • Patients who had upper or lower respiratory tract infections,
  • asthma,
  • a history of allergy,
  • who received isoflurane and desflurane for maintenance of anesthesia,
  • who were the ASA class III-IV,
  • and who had a long uvula,
  • gastroesophageal reflux or sleep apnea,
  • electrolyte disturbances such as hypomagnesemia and hypocalcemia,
  • a BMI (body mass index) over 30 were excluded from the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Van yuzuncu Yıl University, Dursun Odabas Medical Center

Van, 65080, Turkey (Türkiye)

Location

Van yuzuncu Yıl University, Dursun Odabas Medical Center

Van, Turkey (Türkiye)

Location

Related Publications (4)

  • Mao Z, Gao L, Wang G, Liu C, Zhao Y, Gu W, Kang H, Zhou F. Subglottic secretion suction for preventing ventilator-associated pneumonia: an updated meta-analysis and trial sequential analysis. Crit Care. 2016 Oct 28;20(1):353. doi: 10.1186/s13054-016-1527-7.

  • Carter EL, Duguid A, Ercole A, Matta B, Burnstein RM, Veenith T. Strategies to prevent ventilation-associated pneumonia: the effect of cuff pressure monitoring techniques and tracheal tube type on aspiration of subglottic secretions: an in-vitro study. Eur J Anaesthesiol. 2014 Mar;31(3):166-71. doi: 10.1097/EJA.0000000000000009.

  • Alalami AA, Ayoub CM, Baraka AS. Laryngospasm: review of different prevention and treatment modalities. Paediatr Anaesth. 2008 Apr;18(4):281-8. doi: 10.1111/j.1460-9592.2008.02448.x.

  • Yuzkat N, Demir CY. Effect of using the Suction Above Cuff Endotracheal Tube (SACETT) on postoperative respiratory complications in rhinoplasty: a randomized prospective controlled trial. Ther Clin Risk Manag. 2019 Apr 17;15:571-577. doi: 10.2147/TCRM.S200662. eCollection 2019.

MeSH Terms

Conditions

LaryngismusPostoperative Complications

Condition Hierarchy (Ancestors)

Vocal Cord DysfunctionLaryngeal DiseasesRespiratory Tract DiseasesRespiration DisordersOtorhinolaryngologic DiseasesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Nureddin Yüzkat, Assis prof

    Yuzuncu Yil University

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
OTHER
Intervention Model
PARALLEL
Model Details: A randomized prospective controlled study
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant professor

Study Record Dates

First Submitted

June 19, 2018

First Posted

July 12, 2018

Study Start

June 1, 2018

Primary Completion

October 30, 2018

Study Completion

October 30, 2018

Last Updated

December 4, 2018

Record last verified: 2018-12

Locations