Investigation of the Psychometric Properties of the Squares Test in Measuring Hand Function in Parkinson's Disease

NCT03580486 | Completed

• 1 other identifier: 844
• Study Type: observational
• Target: 107
• Locations: 0 countries
• Sites: N/A

Brief Summary

The first aim of the present study was to investigate reliability, validity and responsiveness to the minimal clinically important difference, which is defined as the smallest change in score corresponding to clinically meaningful change realized by patient, of the squares test in people with PD. The second aim of the study is to determine the relationship between hand function and both trunk control and balance in PD population.

Conditions

Parkinson Disease

Keywords

Parkinson's Disease; Hand Function; Squares Test

Outcome Measures

Primary Outcomes (1)

• The Squares Test

  The Squares Test is used to evaluate hand function.

  2 minutes

Secondary Outcomes (3)

• The Nine-Hole Peg Test

  2 minutes

• Berg Balance Scale

  15 minutes

• Trunk Impairment Scale

  20 minutes

Study Arms (2)

Patients with Parkinson's Disease

Parkinson's Disease (Hoehn and Yahr stage 1-4)

Other: The squares test

Healthy controls

Healthy people

Other: The squares test

Interventions

The squares test OTHER

The squares test (ST) originally used in handedness is modified. The ST is a reliable, not time-consuming and easy to administer test for evaluated hand function.

Healthy controls; Patients with Parkinson's Disease

Eligibility Criteria

• Age: 40 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients with Parkinson's Disease who apply to the Dokuz Eylül University Hospital will be invited to this study.

You may qualify if:

• at least 40 years of age
• neurologist-diagnosed idiopathic PD (using UK Brain Bank criteria)
• Hoehn \& Yahr (H\&Y) stages 1 to 4
• Mini-Mental State Examination ≥ 22/30 (literate and with 5 or more years of education) and ≥18/30 (illiterate and with less than 5 years of education)
• living in the community

You may not qualify if:

• individuals with other major diseases (e.g., cancer, stroke, epilepsy, dementia, and severe rheumatoid arthritis)
• preexisting disabilities
• visual impairments
• diagnosis of atypical Parkinsonism
• H\&Y stage 5
• previous surgical management of PD

Sponsors & Collaborators

• Gazi University: lead

Related Publications (9)

• Annett M. Five tests of hand skill. Cortex. 1992 Dec;28(4):583-600. doi: 10.1016/s0010-9452(13)80229-8.

  PMID: 1478086 BACKGROUND

• Verheyden G, Willems AM, Ooms L, Nieuwboer A. Validity of the trunk impairment scale as a measure of trunk performance in people with Parkinson's disease. Arch Phys Med Rehabil. 2007 Oct;88(10):1304-8. doi: 10.1016/j.apmr.2007.06.772.

  PMID: 17908573 BACKGROUND

• Leddy AL, Crowner BE, Earhart GM. Functional gait assessment and balance evaluation system test: reliability, validity, sensitivity, and specificity for identifying individuals with Parkinson disease who fall. Phys Ther. 2011 Jan;91(1):102-13. doi: 10.2522/ptj.20100113. Epub 2010 Nov 11.

  PMID: 21071506 BACKGROUND

• Earhart GM, Cavanaugh JT, Ellis T, Ford MP, Foreman KB, Dibble L. The 9-hole PEG test of upper extremity function: average values, test-retest reliability, and factors contributing to performance in people with Parkinson disease. J Neurol Phys Ther. 2011 Dec;35(4):157-63. doi: 10.1097/NPT.0b013e318235da08.

  PMID: 22020457 BACKGROUND

• Proud EL, Miller KJ, Bilney B, Balachandran S, McGinley JL, Morris ME. Evaluation of measures of upper limb functioning and disability in people with Parkinson disease: a systematic review. Arch Phys Med Rehabil. 2015 Mar;96(3):540-551.e1. doi: 10.1016/j.apmr.2014.09.016. Epub 2014 Oct 7.

  PMID: 25301441 BACKGROUND

• Gebhardt A, Vanbellingen T, Baronti F, Kersten B, Bohlhalter S. Poor dopaminergic response of impaired dexterity in Parkinson's disease: Bradykinesia or limb kinetic apraxia? Mov Disord. 2008 Sep 15;23(12):1701-6. doi: 10.1002/mds.22199.

  PMID: 18649388 BACKGROUND

• Foki T, Vanbellingen T, Lungu C, Pirker W, Bohlhalter S, Nyffeler T, Kraemmer J, Haubenberger D, Fischmeister FP, Auff E, Hallett M, Beisteiner R. Limb-kinetic apraxia affects activities of daily living in Parkinson's disease: a multi-center study. Eur J Neurol. 2016 Aug;23(8):1301-7. doi: 10.1111/ene.13021. Epub 2016 May 1.

  PMID: 27132653 BACKGROUND

• Gillen G, Boiangiu C, Neuman M, Reinstein R, Schaap Y. Trunk posture affects upper extremity function of adults. Percept Mot Skills. 2007 Apr;104(2):371-80. doi: 10.2466/pms.104.2.371-380.

  PMID: 17566426 BACKGROUND

• Schenkman M, Morey M, Kuchibhatla M. Spinal flexibility and balance control among community-dwelling adults with and without Parkinson's disease. J Gerontol A Biol Sci Med Sci. 2000 Aug;55(8):M441-5. doi: 10.1093/gerona/55.8.m441.

  PMID: 10952366 BACKGROUND

MeSH Terms

Conditions

Parkinson Disease

Condition Hierarchy (Ancestors)

Parkinsonian Disorders; Basal Ganglia Diseases; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Movement Disorders; Synucleinopathies; Neurodegenerative Diseases

Study Officials

• Fatih Söke

  Gazi University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: research assistant

Study Record Dates

• First Submitted: June 29, 2018
• First Posted: July 9, 2018
• Study Start: December 19, 2014
• Primary Completion: August 17, 2015
• Study Completion: August 17, 2015
• Last Updated: July 9, 2018

Record last verified: 2018-06

Data Sharing

• IPD Sharing: Will not share