NCT03577821

Brief Summary

Complete arterial coronary artery bypass grafting (CABG) is a surgical option to improve long-term results in the treatment of coronary artery disease (CAD). The goal of coronary artery bypass operations is complete revascularization and there is an increasing interest toward complete arterial revascularization to achieve this goal because of high late failure of saphenous vein graft

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jul 2018

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 8, 2018

Completed
23 days until next milestone

Study Start

First participant enrolled

July 1, 2018

Completed
4 days until next milestone

First Posted

Study publicly available on registry

July 5, 2018

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 30, 2019

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2020

Completed
Last Updated

July 5, 2018

Status Verified

June 1, 2018

Enrollment Period

1.5 years

First QC Date

June 8, 2018

Last Update Submit

July 3, 2018

Conditions

Ischemic Heart Disease

Outcome Measures

Primary Outcomes (1)

  • target vessel revascularization

    readmission for revascularization due to graft failure

    baseline-3 months

Secondary Outcomes (5)

  • Major cardiac events

    baseline-3 months

  • Postoperative morbidity

    3 months

  • Wound infection

    3 months

  • Bleeding

    Early postoperative up to 1 week

  • Length of ICU stay

    Early postoperative up to 1 week

Eligibility Criteria

Age20 Years - 80 Years
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All patients who will be operated in cardiothoracic surgey department Assiut university hospital from July 2018 to december 2019 by performing total arterial revascularization (CABG) will be included in the study.

You may qualify if:

  • All patients who will undergo total arterial revascularization either with single or multi vessel coronary artery disease are to be put in the investigator's study work.

You may not qualify if:

  • there is no any.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (5)

  • Doshi R, Rao G, Shlofmitz E, Donnelly J, Meraj P. Comparison of In-Hospital Outcomes After Percutaneous Revascularization for Peripheral Arterial Disease in Patients With a Body Mass Index of >30 kg/m2 Versus </=30 kg/m2 (from the National Inpatient Sample). Am J Cardiol. 2017 Nov 1;120(9):1648-1652. doi: 10.1016/j.amjcard.2017.07.065. Epub 2017 Jul 31.

    PMID: 28842147BACKGROUND

  • Raja SG, Ilsley C, De Robertis F, Lane R, Kabir T, Bahrami T, Simon A, Popov A, Dalby MC, Mason M, Grocott-Mason R, Smith RD, Iqbal MB. Mid-to-long term mortality following surgical versus percutaneous coronary revascularization stratified according to stent subtype: An analysis of 6,682 patients with multivessel disease. PLoS One. 2018 Feb 6;13(2):e0191554. doi: 10.1371/journal.pone.0191554. eCollection 2018.

    PMID: 29408926BACKGROUND

  • Schwann TA, Tatoulis J, Puskas J, Bonnell M, Taggart D, Kurlansky P, Jacobs JP, Thourani VH, O'Brien S, Wallace A, Engoren MC, Tranbaugh RF, Habib RH. Worldwide Trends in Multi-arterial Coronary Artery Bypass Grafting Surgery 2004-2014: A Tale of 2 Continents. Semin Thorac Cardiovasc Surg. 2017 Autumn;29(3):273-280. doi: 10.1053/j.semtcvs.2017.05.018. Epub 2017 Aug 8.

    PMID: 29195570BACKGROUND

  • Buttar SN, Yan TD, Taggart DP, Tian DH. Long-term and short-term outcomes of using bilateral internal mammary artery grafting versus left internal mammary artery grafting: a meta-analysis. Heart. 2017 Sep;103(18):1419-1426. doi: 10.1136/heartjnl-2016-310864. Epub 2017 Jun 23.

    PMID: 28646103BACKGROUND

  • Saraiva J, Antunes PE, Antunes MJ. Coronary artery bypass surgery in young adults: excellent perioperative results and long-term survival. Interact Cardiovasc Thorac Surg. 2017 May 1;24(5):691-695. doi: 10.1093/icvts/ivw407.

    PMID: 28453797BACKGROUND

MeSH Terms

Conditions

Myocardial Ischemia

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular DiseasesVascular Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant lecturer cardiac surgery

Study Record Dates

First Submitted

June 8, 2018

First Posted

July 5, 2018

Study Start

July 1, 2018

Primary Completion

December 30, 2019

Study Completion

February 1, 2020

Last Updated

July 5, 2018

Record last verified: 2018-06