NCT04970017

Brief Summary

To verify whether GLS and LV mechanical dispersion, measured by two-dimensional speckle-tracking echocardiography (2D-STE) correlate with LV scar burden measured by cardiac MRI in patients with ischemic heart disease.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
51

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jan 2021

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2021

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

July 16, 2021

Completed
5 days until next milestone

First Posted

Study publicly available on registry

July 21, 2021

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2022

Completed
Last Updated

July 21, 2021

Status Verified

February 1, 2021

Enrollment Period

1 year

First QC Date

July 16, 2021

Last Update Submit

July 16, 2021

Conditions

Ischemic Heart Disease

Outcome Measures

Primary Outcomes (1)

  • Scare burden by echocardiography

    To test the correlation between the scar burden measured by cardiac MRI and GLS measured by 2D STE

    One year

Secondary Outcomes (1)

  • Value of spickle tracking echocardiography in clinical practice

    One year

Interventions

Cardiac MRI, EchocardiographyRADIATION

Magnetic resonance imaging, Echocardiography

Eligibility Criteria

Sexall
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients presenting for viability assessment in to cardiac MRI unit, Assiut university heart hospital, with a history of previous stemi, at least 3 months after the acute event ( scar stabilization) and up to one year

You may qualify if:

  • Patients presenting for viability assessment in to cardiac MRI unit, Assiut university heart hospital, with a history of previous stemi, at least 3 months after the acute event ( scar stabilization) and up to one year

You may not qualify if:

  • Patients with:
  • Contraindication to cardiac MRI (claustrophobia, Patients with eGFR below 30 mL/min/1.73 m2. and patients with metallic implants)
  • Non-ischemic cardiomyopathy.
  • Valvular heart disease (VHD).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Assiut university

Asyut, 71511, Egypt

RECRUITING

MeSH Terms

Conditions

Myocardial Ischemia

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular DiseasesVascular Diseases

Study Officials

  • Mohamed Abdellatif

    Assiut University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Mohamed Abdellatif, MSC

CONTACT

+201001073747mohamed.abdellatief@med.au.edu.eg

Shimaa Sayed Khidr, PHD

CONTACT

+201001346551S.khidr@aun.edu.eg

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr

Study Record Dates

First Submitted

July 16, 2021

First Posted

July 21, 2021

Study Start

January 1, 2021

Primary Completion

January 1, 2022

Study Completion

January 1, 2022

Last Updated

July 21, 2021

Record last verified: 2021-02

Locations

EG(1)