NCT03573856

Brief Summary

This study will evaluate a behavioral intervention designed to reduce risk factors for type 2 diabetes in American Indian youth aged 7-10 years.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
188

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jul 2018

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 21, 2018

Completed
1 month until next milestone

First Posted

Study publicly available on registry

June 29, 2018

Completed
2 days until next milestone

Study Start

First participant enrolled

July 1, 2018

Completed
5.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2023

Completed
Last Updated

November 21, 2022

Status Verified

November 1, 2022

Enrollment Period

5.2 years

First QC Date

May 21, 2018

Last Update Submit

November 17, 2022

Conditions

Outcome Measures

Primary Outcomes (2)

  • Change from 0 to 12 months in Body Mass Index (BMI)

    12 months

  • Change from 0 to 12 months in fasting insulin

    12 months

Secondary Outcomes (4)

  • Change from 0 to 12 months in BMI z-score

    12 months

  • Change from 0 to 12 months in waist circumference

    12 months

  • Change from 0 to 12 months in hemoglobin A1c

    12 months

  • Change from 0 to 12 months in fasting glucose

    12 months

Other Outcomes (7)

  • Change from 0 to 12 months in fruit/vegetable intake

    12 months

  • Change from 0 to 12 months in physical activity

    12 months

  • Change from 0 to 12 months in screen time

    12 months

  • +4 more other outcomes

Study Arms (2)

Active Living

ACTIVE COMPARATOR

Three component behavioral intervention consisting of group-based classes, individual motivational interviewing-based sessions, and resource toolbox

Behavioral: Active Living

Health and Safety

PLACEBO COMPARATOR

One component health and safety program consisting of group classes

Other: Health and Safety

Interventions

Active LivingBEHAVIORAL

Participants will be provided with education and support for diet and lifestyle modification related to healthy eating and active living.

Active Living

Participants will be provided with education related to general health and safety topics.

Health and Safety

Eligibility Criteria

Age7 Years - 10 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • self-identify as American Indian
  • BMI \>=85th percentile for age and sex
  • have at least one parent/primary caregiver (parent) willing to actively participate

You may not qualify if:

  • diabetes
  • any serious youth/parent health concerns that would interfere with participation
  • plans to move out of the area during the study period

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Childrens Hospital Colorado

Aurora, Colorado, 80045, United States

Location

MeSH Terms

Conditions

OverweightObesity

Interventions

HealthSafety

Condition Hierarchy (Ancestors)

OvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Population CharacteristicsAccident PreventionAccidentsPublic HealthEnvironment and Public Health

Study Officials

  • Katherine Sauder, PhD

    University of Colorado, Denver

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 21, 2018

First Posted

June 29, 2018

Study Start

July 1, 2018

Primary Completion

September 1, 2023

Study Completion

September 1, 2023

Last Updated

November 21, 2022

Record last verified: 2022-11

Locations