NCT03562858

Brief Summary

PICOT elements:P: Teeth restored with indirect tooth colored restoration I: Immediate dentin sealing using universal adhesive C: Delayed dentin sealing O: Post-operative Hypersensitivity T: -Hypersensitivity assessment one week during provisionalization period and post-cementation S: Randomized Controlled Clinical Trial

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
54

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2018

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 16, 2018

Completed
1 month until next milestone

First Posted

Study publicly available on registry

June 20, 2018

Completed
11 days until next milestone

Study Start

First participant enrolled

July 1, 2018

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2018

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2018

Completed
Last Updated

June 20, 2018

Status Verified

June 1, 2018

Enrollment Period

2 months

First QC Date

May 16, 2018

Last Update Submit

June 8, 2018

Conditions

Outcome Measures

Primary Outcomes (3)

  • Post-operative hypersensitivity at baseline

    The post-operative hypersensitivity assessment will be performed at baseline , using visual analogue scale (VAS) for both intervention and control group . The visual analogue scale is a scale numbered from zero to 10 , where as the range from zero to three resembles from no to very mild sensitivity , the range from four to seven resembles moderate sensitivity and from eight to ten resembles severe sensitivity

    10 minutes

  • Post-operative hypersensitivity one week after temporization

    The post-operative hypersensitivity will be assessed one week after temporization for both intervention and control group using the visual analogue scale VAS .The visual analogue scale is a scale numbered from zero to 10 , where as the range from zero to three resembles from no to very mild sensitivity , the range from four to seven resembles moderate sensitivity and from eight to ten resembles severe sensitivity

    1 week

  • Post-operative hypersensitivity after cementation of the indirect tooth coloured restoration

    The post-operative hypersensitivity will be assessed using visual analogue scale VAS 1 week after cementation of the indirect tooth coloured restoration. The visual analogue scale is a scale numbered from zero to 10 , where as the range from zero to three resembles from no to very mild sensitivity, the range from four to seven resembles moderate sensitivity and from eight to ten resembles severe sensitivity

    1 week

Study Arms (2)

Delayed dentine sealing

ACTIVE COMPARATOR
Procedure: Delayed dentin sealing protocol

Immediate dentin sealing

EXPERIMENTAL
Procedure: Immediate dentin sealing protocol

Interventions

Sealing of the dentin before impression taking directly after cavity preparation to prevent postoperative hypersensitivity during provisionalization and after cementation

Immediate dentin sealing

Sealing the dentin just prior to cementation

Delayed dentine sealing

Eligibility Criteria

Age18 Years - 50 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Extensive carious lesions indicated for indirect restorations
  • Lower first molars
  • Age of patients range is 18 -50 years
  • Patients have not received antibiotic therapy for 1 month before sampling
  • Males or Females (Both genders)
  • Patients with Good oral hygiene
  • Co-operative patients approving the trial

You may not qualify if:

  • Pregnancy
  • Systemic disease or severe medical
  • Patients having complications as:
  • Periodontal problems Mobile teeth, arrest caries and non-vital teeth
  • Heavy smoking patients
  • Xerostomia
  • Lack of compliance

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of dentistry cairo university

Cairo, 002, Egypt

Location

MeSH Terms

Conditions

Dentin Sensitivity

Condition Hierarchy (Ancestors)

Tooth DiseasesStomatognathic Diseases

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principle investigator

Study Record Dates

First Submitted

May 16, 2018

First Posted

June 20, 2018

Study Start

July 1, 2018

Primary Completion

September 1, 2018

Study Completion

October 1, 2018

Last Updated

June 20, 2018

Record last verified: 2018-06

Locations