Effects of Resistance Training on Physical Performance, Health and Quality of Life in Elderly (RTCHealth)

NCT03551132 | Completed

• 1 other identifier: UC PMAFI/03/12
• Study Type: interventional
• Target: 45
• Locations: 1 country
• Sites: 1

Brief Summary

Physical exercise is considered an important intervention for promoting well-being and healthy aging. The purpose of the present study was to determine the effects of moderate-to-high intensity resistance training circuit on different parameters of fat mass, functional autonomy, strength and quality of life in elderly. A randomized controlled trial was conducted. A total of 45 subjects, (27 females, 18 males) aged between 65-75 years old from Murcia (Spain) were randomly to experimental group (resistance training circuit for 12-weeks and isocaloric diet program) and control group (no resistance training intervention). Fat mass, functional autonomy, muscular strength, perceived exertion, and quality of life perception were obtained with validated tools. Experimental group decreases significantly their fat mass percentage whilst control group not presented differences. Muscular strength results exhibited significant differences between intervention training protocol. Furthermore, experimental group presented better marks than control group at quality of life questionnaire and functional autonomy scores. The moderate-to-high intensity resistance training circuit showed increase in upper and lower muscular strength as well as functional capacity and significantly decreased total fat mass and that improvements in physical function predict improvements in QoL perception in elderly.

Conditions

Sarcopenia; Body Weight Changes; Quality of Life

Keywords

elderly; resistance training; health

Outcome Measures

Primary Outcomes (7)

• body weight in kilograms

  was measured after removal of shoes and heavy outer clothing, using a Tanita BC-418 MA (Tanita Corporation, Arlington Heights, IL) to the nearest 0.1 kg.

  Change from Baseline body weight (kg) at 12 weeks

• height in meters

  Standing height without shoes was measured using a Seca 202 stadiometer (Seca, Hamburg, Germany) to the nearest 0.1 cm.

  Change from Baseline standing height (cm) at 12 weeks

• Body Mass Index (BMI)

  was calculated as the ratio of weight to squared height in kg/m\^2

  Change from Baseline Body Mass Index (BMI): (kg/m^2) at 12 weeks

• % Fat mass

  % fat mass was measured after removal of shoes and heavy outer clothing, using a Tanita BC-418 MA (Tanita Corporation, Arlington Heights, IL) to the nearest 0.1 kg.

  Change from Baseline bioelectrical impedance % fat mass at 12 weeks

• Quality of life

  Quality of Life in the elderly (WHOQOL-OLD) is an instrument developed by Power et al., translated and validated for the Spanish language. The WHOQOL-OLD is a 24-item self-report instrument that is divided into six Facets. Is also calculated from the set of 24 items. Answers are based on a 5-point Likert response scale

  Change from Baseline Quality of Life perception at 12 weeks

• Functional autonomy

  The Latin American Group for Maturity (GDLAM) protocol was used to evaluate functional autonomy. It is composed of five tests: W10m; SSP; SPP; SCMA; PTS. These tests are used in a mathematical formula to calculate the GDLAM index (GI).

  Change from Baseline Functional autonomy at 12 weeks

• Muscular strength

  The predicted 1-repetition maximum (1-RM) testing protocol followed the procedure previously described by Brzycki. Upper body muscles strength and lower body strength was measured

  Change from Baseline Muscular Strength at 12 weeks

Study Arms (2)

Group 1

EXPERIMENTAL

Experimental group A supervised progressive moderate-to-high RTC program designed to induce muscular hypertrophy was performed. EG followed a progressive moderate-to-high RTC program for 12-weeks. The training program incorporated resistance exercise of six major regions and consisted of 3 training sessions per week on non-consecutive days (Monday, Wednesday and Friday). All subjects performed the sets with moderate-intensity (8 to 12 repetitions) in each exercise and 30-60 seconds rest between sets. The load was increased during the 12 weeks from 60% 1-RM to high-intensity 80% 1-RM. The training load was increased when the individual could perform more than the prescribed number of repetitions (12 repetitions) followed the OMNI-RES scale and a hard effort perception level. Rest between sets was 1-2 minutes.

Other: Exercise test

Group 2

NO INTERVENTION

Control group The CG not participated in the RTC program.

Interventions

Exercise test OTHER

Fat mass, Functional autonomy, muscular strength, quality of life questionnaire

Group 1

Eligibility Criteria

• Age: 65 Years - 75 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)

You may qualify if:

• Age ≥ 65 years.
• Never attended classes of fitness academies or following Physical Activity.
• No experience in Resistance Training.

You may not qualify if:

• No history of neuromuscular, metabolic, hormonal, cardiovascular diseases.
• Not taking any medication that could influence hormonal and neuromuscular metabolism.

Sponsors & Collaborators

• Universidad Católica San Antonio de Murcia: lead

Study Sites (1)

Pablo Jorge Marcos Pardo

Murcia, 30011, Spain

Location

MeSH Terms

Conditions

Sarcopenia; Body Weight Changes

Interventions

Exercise Test

Condition Hierarchy (Ancestors)

Muscular Atrophy; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Signs and Symptoms; Body Weight

Intervention Hierarchy (Ancestors)

Heart Function Tests; Diagnostic Techniques, Cardiovascular; Diagnostic Techniques and Procedures; Diagnosis; Respiratory Function Tests; Diagnostic Techniques, Respiratory System; Ergometry; Investigative Techniques

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Model Details: A randomized controlled trial

Study Record Dates

• First Submitted: May 15, 2018
• First Posted: June 11, 2018
• Study Start: May 15, 2018
• Primary Completion: May 15, 2018
• Study Completion: May 15, 2018
• Last Updated: June 11, 2018

Record last verified: 2018-05

Data Sharing

• IPD Sharing: Will not share

Locations

ES (1)