NCT03546647

Brief Summary

This study seeks to quantify digital visual performance and subjective visual acceptance of toric contact lenses as compared to spherical lenses in low to moderate astigmatic patients.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
35

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jun 2018

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 18, 2018

Completed
19 days until next milestone

First Posted

Study publicly available on registry

June 6, 2018

Completed
12 days until next milestone

Study Start

First participant enrolled

June 18, 2018

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 21, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 21, 2018

Completed
2.5 years until next milestone

Results Posted

Study results publicly available

June 7, 2021

Completed
Last Updated

June 7, 2021

Status Verified

June 1, 2021

Enrollment Period

6 months

First QC Date

May 18, 2018

Results QC Date

January 7, 2021

Last Update Submit

June 4, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • Near Visual LogMAR Acuity

    High contrast LogMAR visual acuity was assessed at 40 cm using the M\&S Clinical Trial Suite system (Niles, Illinois, USA). The system was calibrated according to the manufacturer's directions every day, prior to use. Testing was performed binocularly. The test started at 20/200 and continued until three letters were missed on a line.

    10 +/- 2 days

Study Arms (2)

Toric, Then Sphere

EXPERIMENTAL

Participants who received Toric contact lenses first and spherical lenses after 10 days

Device: Dailies Aqua Comfort Plus ToricDevice: Dailies Aqua Comfort Plus Sphere

Sphere, Then Toric

EXPERIMENTAL

Participants who received Spherical contact lenses first and Toric lenses after 10 days

Device: Dailies Aqua Comfort Plus ToricDevice: Dailies Aqua Comfort Plus Sphere

Interventions

Daily disposable soft toric contact lens

Sphere, Then ToricToric, Then Sphere

Daily disposable soft spherical contact lens

Sphere, Then ToricToric, Then Sphere

Eligibility Criteria

Age18 Years - 39 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • +6.00 to -6.00 D vertexed sphere power and -0.75 to -1.50 D vertexed refractive cylinder in the right and left eyes Best corrected acuity of 20/25 or better in each eye Self report of at least 4 hrs/day using digital devices Current/established soft contact lens wearer (has worn contact lenses in the past year)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Houston College of Optometry

Houston, Texas, 77204, United States

Location

MeSH Terms

Conditions

Astigmatism

Condition Hierarchy (Ancestors)

Refractive ErrorsEye Diseases

Results Point of Contact

Title
Kathryn Richdale OD, PhD
Organization
University of Houston

Study Officials

  • Kathryn Richdale, OD, PhD

    University of Houston College of Optometry

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

May 18, 2018

First Posted

June 6, 2018

Study Start

June 18, 2018

Primary Completion

December 21, 2018

Study Completion

December 21, 2018

Last Updated

June 7, 2021

Results First Posted

June 7, 2021

Record last verified: 2021-06

Data Sharing

IPD Sharing
Will not share

Locations