The Effects of a Jump Rope Exercise Program on Vascular Health, Inflammatory Markers in Prehypertensive Adolescent Girls

NCT03534427 | Completed Results

• 1 other identifier: PusanNU1
• Study Type: interventional
• Target: 40
• Locations: 0 countries
• Sites: N/A

Brief Summary

The purpose of this study was to examine the impact of a 12-week jump rope exercise program on blood pressure, arterial stiffness, vasodilating and vasoconstricting factors, inflammatory markers, and body composition in prehypertensive adolescent girls. Forty prehypertensive adolescent girls participated in this study. The girls were randomly divided into the jump rope exercise intervention group (EX, n=20) and control group (CON, n=20). The EX group performed a jump rope training program at 40-70% of their heart rate reserve (HRR) 5 days/week for 12 weeks (sessions 50 minutes in duration). The CON group did not participate in any structured or unstructured exercise protocol. Blood pressure, arterial stiffness, plasma nitrate/nitrite levels, endothelin-1, C-reactive protein, and body composition were measured before and after the 12-weeks study.

Conditions

Prehypertension; Blood Pressure; Abdominal Obesity; Adiposity

Keywords

arterial stiffness; endothelin-1; c-reactive protein; adiposity; exercise; jump rope

Outcome Measures

Primary Outcomes (11)

• Arterial Stiffness

  Arterial stiffness was measured as measurement of brachial to ankle pulse-wave velocity. This indicates peripheral arterial stiffness, as it measures how quickly a pulse wave propagates from one point to another.

  12 weeks

• Endothelin-1

  Levels of Endothelin-1 in blood were measured by Endothelin-1 enzyme immunoassay kit.

  12 weeks

• Body Mass

  Body mass was measured to nearest 0.1 kg.

  12 weeks

• Height

  Height was measured to nearest 1 cm.

  12 weeks

• Waist Circumference

  Waist circumference was measured at midpoint between the lower rib and the iliac crest at the end of a normal expiration using a tape measure.

  12 weeks

• Body Fat

  Percent body fat (%) was determined using a bioelectrical impedance-meter.

  12 weeks

• Lean Body Mass

  Lean body mass (kg) was determined using a bioelectrical impedance-meter.

  12 weeks

• Nitrate/Nitrite Levels

  Nitrate and nitrite levels were assayed using a Griess assay kit.

  12 weeks

• C-reactive Protein

  C-reactive protein was assessed using an enzyme immunoassay assay kit

  12 weeks

• Systolic Blood Pressure

  Blood pressure was measured in duplicate using an automated sphygmomanometer. The average of the two was recorded as the resting blood pressure.

  12 weeks

• Diastolic Blood Pressure

  12 weeks

Study Arms (2)

Control group

NO INTERVENTION

No exercise intervention

Jump rope exercise intervention

EXPERIMENTAL

The jump rope exercise program was performed for 50 minutes with 5 minutes of warm-up and cool-down per day, 5 times a week for 12 weeks. The program consisted of various main jump rope exercises (1 line 2 jump, jumping feet together, running jumping, open side jump, open back and forth jump, rock paper scissor jump). The warm-up and cool down consisted of static stretching, walking, and jogging. Intensity of exercise was gradually increased from 40-50% heart rate reserve (HRR) in weeks 1-4 and to 60-70% HRR in weeks 9-12. Each training session was supervised by the researchers. Every subject wore a heart rate monitor during the whole training session in order to maintain the designated training intensity.

Other: Jump rope exercise intervention

Interventions

Jump rope exercise intervention OTHER

12-week jump rope exercise program

Jump rope exercise intervention

Eligibility Criteria

• Age: 14 Years - 16 Years
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)

You may qualify if:

• prehypertensive
• sedentary (no regular exercise training or physical activity within the last year)
• no weight loss diet during the last six months

You may not qualify if:

• pregnancy
• chronic disease
• daily medication use (including antioxidants and weight loss supplements)

Sponsors & Collaborators

• Pusan National University: lead

MeSH Terms

Conditions

Prehypertension; Obesity, Abdominal; Obesity; Motor Activity

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases; Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Behavior

Results Point of Contact

• Title: Dr. Song-Young Park
• Organization: The University of Nebraska at Omaha

song-youngpark@unomaha.edu

402-554-3374

Publication Agreements

• PI is Sponsor Employee: Yes

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Model Details: exercise intervention group, control group

Study Record Dates

• First Submitted: May 11, 2018
• First Posted: May 23, 2018
• Study Start: June 5, 2011
• Primary Completion: February 10, 2012
• Study Completion: March 21, 2012
• Last Updated: October 29, 2020
• Results First Posted: August 14, 2019

Record last verified: 2020-10

Data Sharing

• IPD Sharing: Will not share