NCT03530618

Brief Summary

The purpose of this study is to compare the differences in central venous catheter insertion time, success rate, and complication between the flexible tip straight guidewire and J-tip guidewire for ultrasound-guided central venous catheterization in small children.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
88

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Sep 2018

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 8, 2018

Completed
13 days until next milestone

First Posted

Study publicly available on registry

May 21, 2018

Completed
4 months until next milestone

Study Start

First participant enrolled

September 6, 2018

Completed
2.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2021

Completed
Last Updated

September 20, 2021

Status Verified

September 1, 2021

Enrollment Period

2.8 years

First QC Date

May 8, 2018

Last Update Submit

September 13, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • First successful central venous catheterization rate

    Interval between skin penetration of the needle and installation of the indwelling catheter, an expected average of 3 minutes

Secondary Outcomes (7)

  • Time to first puncture of central vein

    Interval between skin penetration of the needle and flashback of blood, an expected average of 30 seconds

  • Time to guide wire insertion

    Interval between skin penetration and removal of the needle after guide wire insertion, an expected average of 90 seconds

  • Total time to central venous catheterization

    Interval between skin penetration of the needle and installation of the indwelling catheter, an expected average of 3 minutes

  • Number of central vein puncture trial

    up to 5 times, an expected average observation time of 30 seconds

  • Number of guide wire insertion trial

    up to 5 times, an expected average observation time of 90 seconds

  • +2 more secondary outcomes

Study Arms (2)

Flexible tip straight guidewire

EXPERIMENTAL
Device: Flexible tip straight guidewire

J-tip guidewire

EXPERIMENTAL
Device: J-tip

Interventions

Use a flexible tip straight guidewire for ultrasound-guided central venous catheterization

Flexible tip straight guidewire
J-tipDEVICE

Use a J tip straight guidewire for ultrasound-guided central venous catheterization

J-tip guidewire

Eligibility Criteria

AgeUp to 6 Months
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • surgery under general anesthesia
  • require central venous catheterization

You may not qualify if:

  • central vein anomaly
  • hematoma in central vein
  • catheterization site infection

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Seoul National University Hospital

Seoul, 03080, South Korea

Location

Related Publications (1)

  • Kim EH, Kang P, Song IS, Ji SH, Jang YE, Lee JH, Kim HS, Kim JT. Straight-tip guidewire versus J-tip guidewire for central venous catheterisation in neonates and small infants: A randomised controlled trial. Eur J Anaesthesiol. 2022 Aug 1;39(8):656-661. doi: 10.1097/EJA.0000000000001695. Epub 2022 Jul 7.

Study Officials

  • Jin-Tae Kim, Professor

    Seoul National University Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
professor

Study Record Dates

First Submitted

May 8, 2018

First Posted

May 21, 2018

Study Start

September 6, 2018

Primary Completion

July 1, 2021

Study Completion

July 1, 2021

Last Updated

September 20, 2021

Record last verified: 2021-09

Locations