NCT03528759

Brief Summary

Streptococcus pseudopneumoniae as suggested by DNA-DNA homology studies is recorded as a species of the Streptococcus mitis/oralis members of viridans group Streptococci; they have some similar features to the Streptococcus mitis/oralis members of viridans Streptococcus pneumoniae

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jul 2019

Shorter than P25 for all trials

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 26, 2018

Completed
2 months until next milestone

First Posted

Study publicly available on registry

May 18, 2018

Completed
1.1 years until next milestone

Study Start

First participant enrolled

July 1, 2019

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2019

Completed
2 days until next milestone

Study Completion

Last participant's last visit for all outcomes

August 3, 2019

Completed
Last Updated

February 5, 2019

Status Verified

May 1, 2018

Enrollment Period

1 month

First QC Date

March 26, 2018

Last Update Submit

February 3, 2019

Conditions

PneumoniaStreptococcus Infection

Outcome Measures

Primary Outcomes (1)

  • identification of Streptococcus. pseudopneumoniae

    Streptococcus will be identified by polymerase chain Reaction under complete aseptic condition

    1year

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Sputum samples will be collected from all studied patients under complete aseptic condition. sputum specimens will be cultivated on 5% sheep blood agar, chocolate agar (Oxoid, UK.

You may qualify if:

  • All patients showing signs of respiratory tract infection

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (3)

  • Raddaoui A, Simoes AS, Baaboura R, Felix S, Achour W, Ben Othman T, Bejaoui M, Sa-Leao R, Ben Hassen A. Serotype Distribution, Antibiotic Resistance and Clonality of Streptococcus pneumoniae Isolated from Immunocompromised Patients in Tunisia. PLoS One. 2015 Oct 13;10(10):e0140390. doi: 10.1371/journal.pone.0140390. eCollection 2015.

    PMID: 26461259RESULT

  • Charalambous BM. Identifying divergent streptococcal strains using pherotype: implications for pathogen emergence and epidemiology. Future Microbiol. 2012 Dec;7(12):1349-54. doi: 10.2217/fmb.12.114.

    PMID: 23231485RESULT

  • Leung MH, Ling CL, Ciesielczuk H, Lockwood J, Thurston S, Charalambous BM, Gillespie SH. Streptococcus pseudopneumoniae identification by pherotype: a method to assist understanding of a potentially emerging or overlooked pathogen. J Clin Microbiol. 2012 May;50(5):1684-90. doi: 10.1128/JCM.00131-12. Epub 2012 Feb 29.

    PMID: 22378913RESULT

MeSH Terms

Conditions

PneumoniaStreptococcal Infections

Condition Hierarchy (Ancestors)

Respiratory Tract InfectionsInfectionsLung DiseasesRespiratory Tract DiseasesGram-Positive Bacterial InfectionsBacterial InfectionsBacterial Infections and Mycoses

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principle Investigator

Study Record Dates

First Submitted

March 26, 2018

First Posted

May 18, 2018

Study Start

July 1, 2019

Primary Completion

August 1, 2019

Study Completion

August 3, 2019

Last Updated

February 5, 2019

Record last verified: 2018-05

Data Sharing

IPD Sharing
Will not share