Predictors of Mortality Among Ventilator Associated Pneumonia Patients

NCT06246994 | Not Yet Recruiting

• 1 other identifier: Predictors of vap mortality
• Study Type: observational
• Target: 140
• Locations: 0 countries
• Sites: N/A

Brief Summary

In this context, this study aims to explore the risk factors for mortality from VAP in respiratory ICU.

Conditions

Pneumonia

Outcome Measures

Primary Outcomes (2)

• Mortality rate at 28 days.

  Evaluation of number of dead patients from vap wihin 28 days of infection and

  28 days

• Percentage of risk factors of VAP mortality.

  Search for risk factors for mortality of vap wihin 28 days of infection.

  28 days

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

This study will enroll adult participants over 18 years old who had undergone mechanical ventilation for longer than 48 hours. Only the first episode of VAP for each patient will be included.

You may qualify if:

• adult participants over 18 years old who had undergone mechanical ventilation for longer than 48 hours.
• Only the first episode of VAP for each patient will be included.

You may not qualify if:

• Patients who are less than 18 years old.
• Pneumonia diagnosed before mechanical ventilation.

Sponsors & Collaborators

• Assiut University: lead

Related Publications (5)

• Vincent JL, Sakr Y, Singer M, Martin-Loeches I, Machado FR, Marshall JC, Finfer S, Pelosi P, Brazzi L, Aditianingsih D, Timsit JF, Du B, Wittebole X, Maca J, Kannan S, Gorordo-Delsol LA, De Waele JJ, Mehta Y, Bonten MJM, Khanna AK, Kollef M, Human M, Angus DC; EPIC III Investigators. Prevalence and Outcomes of Infection Among Patients in Intensive Care Units in 2017. JAMA. 2020 Apr 21;323(15):1478-1487. doi: 10.1001/jama.2020.2717.

  PMID: 32207816 RESULT

• Zhou XY, Ben SQ, Chen HL, Ni SS. A comparison of APACHE II and CPIS scores for the prediction of 30-day mortality in patients with ventilator-associated pneumonia. Int J Infect Dis. 2015 Jan;30:144-7. doi: 10.1016/j.ijid.2014.11.005. Epub 2014 Nov 12.

  PMID: 25461659 RESULT

• Arayasukawat P, So-Ngern A, Reechaipichitkul W, Chumpangern W, Arunsurat I, Ratanawatkul P, Chuennok W. Microorganisms and clinical outcomes of early- and late-onset ventilator-associated pneumonia at Srinagarind Hospital, a tertiary center in Northeastern Thailand. BMC Pulm Med. 2021 Jan 30;21(1):47. doi: 10.1186/s12890-021-01415-8.

  PMID: 33516213 RESULT

• John AO, Paul H, Vijayakumar S, Anandan S, Sudarsan T, Abraham OC, Balaji V. Mortality from acinetobacter infections as compared to other infections among critically ill patients in South India: A prospective cohort study. Indian J Med Microbiol. 2020 Jan-Mar;38(1):24-31. doi: 10.4103/ijmm.IJMM_19_492.

  PMID: 32719205 RESULT

• Zimmerman JE, Kramer AA, McNair DS, Malila FM, Shaffer VL. Intensive care unit length of stay: Benchmarking based on Acute Physiology and Chronic Health Evaluation (APACHE) IV. Crit Care Med. 2006 Oct;34(10):2517-29. doi: 10.1097/01.CCM.0000240233.01711.D9.

  PMID: 16932234 RESULT

MeSH Terms

Conditions

Pneumonia

Condition Hierarchy (Ancestors)

Respiratory Tract Infections; Infections; Lung Diseases; Respiratory Tract Diseases

Study Officials

• Doaa Magdy, assisst -professor

  Assiut University

  STUDY DIRECTOR

Central Study Contacts

Marwa Kilany, Assisst- lecture

CONTACT

01064123545; docmero1693@gmail.com

Saher Mahmoud, lecture

CONTACT

01002866364; farida62014@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principal investigator

Study Record Dates

• First Submitted: January 17, 2024
• First Posted: February 7, 2024
• Study Start: March 1, 2024
• Primary Completion: March 1, 2025
• Study Completion: September 1, 2025
• Last Updated: February 13, 2024

Record last verified: 2024-02