Association of Synchronous Four-limb blOod pRessure and Pulse Wave velocIty With Cardiovascular Events
ASORPWICE
A National Registry for the Association of Synchronous Four-limb Blood Pressure and Pulse Wave Velocity With Cardiovascular Events in China
1 other identifier
observational
100,000
1 country
19
Brief Summary
A multicenter prospective registry planned to recruit more than 100 000 patients 50 years old and older was carried out in China. This primary purpose of this study was to evaluate the association of synchronous four-limb blood pressure and pulse wave velocity with cardiovascular events. The secondary purpose was to evaluate the incidence rate,prevalence rate, value of diagnosis for peripheral arterial occlusive disease, and to follow up the effects of revascularization on cardiovascular events.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2018
Longer than P75 for all trials
19 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2018
CompletedFirst Submitted
Initial submission to the registry
April 11, 2018
CompletedFirst Posted
Study publicly available on registry
May 11, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
December 31, 2023
CompletedMay 11, 2018
April 1, 2018
5 years
April 11, 2018
April 28, 2018
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Incidence of cardiovascular events (cardiovascular death,myocardial infarction, heart failure, stroke, renal failure, aortic dissection)
From date of enrollment until the date of first documented cardiovascular events or date of death from any cause, whichever came first, assessed up to 12 months
Secondary Outcomes (5)
Incidence of cardiovascular events (cardiovascular death,myocardial infarction, heart failure, stroke, renal failure, aortic dissection)
Measured at 6 months, 24 months and every 12 months thereafter from date of enrollment until the date of first documented cardiovascular events or date of death from any cause, whichever came first, assessed up to 60 months
Incidence of death from any cause
Measured at 6 months, 12 months and every 12 months thereafter from date of enrollment until the date of first documented death from any cause, assessed up to 60 months
Incidence of peripheral arterial disease
Measured at 6 months, 12 months and every 12 months thereafter from date of enrollment until the date of first documented four-limb peripheral arterial disease or date of death from any cause, whichever came first, assessed up to 60 months
Incidence of limb gangrene
Measured at 6 months, 12 months and every 12 months thereafter from date of enrollment until the date of first documented gangrene caused by peripheral arterial disease or date of death from any cause,whichever came first, assessed up to 60 months
Incidence of amputation
Measured at 6 months, 12 months and every 12 months thereafter from date of enrollment until the date of first documented amputation caused by peripheral arterial disease or date of death from any cause, whichever came first, assessed up to 60 months
Eligibility Criteria
Chinese populations with age ≥ 50 years old at the time of informed consent in hospital, community and physical examination center
You may qualify if:
- Age ≥ 50 years old at the time of informed consent
- Chinese populations in hospital, community and physical examination center
You may not qualify if:
- Patients with lack of limb,malformation of limbs, severe limb trauma or infection.
- Serious organic disease affecting the quality of life, such as tumors, massive cerebral infarction, uremia, and etc.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (19)
Beijing Renhe Hospital
Beijing, Beijing Municipality, 010, China
Chinese PLA General Hospital
Beijing, Beijing Municipality, 010, China
Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College
Beijing, Beijing Municipality, 010, China
Daping Hospital
Chongqing, Chongqing Municipality, 023, China
The Second Affiliated Hospital of Chongqing Medical University
Chongqing, Chongqing Municipality, 023, China
Lanzhou University Second Hospital
Lanzhou, Gansu, 0931, China
Guangdong General Hospital
Guangzhou, Guangdong, 020, China
The Eighth Affiliated Hospital of Sun Yat-sen University
Shenzhen, Guangdong, 0755, China
Kailuan General Hospital
Tangshan, Hebei, 0315, China
The First Affiliated Hospital of Nanchang University
Nanchang, Jiangxi, 0791, China
The Second Affiliated Hospital of Nanchang University
Nanchang, Jiangxi, 0791, China
The General Hospital of Shenyang Military
Shenyang, Liaoning, 024, China
Ruijin Hospital, Shanghai Jiaotong University School of Medicine
Shanghai, Shanghai Municipality, 021, China
Shanghai East Hospital
Shanghai, Shanghai Municipality, 021, China
Shanxi Cardiovascular Hospital
Taiyuan, Shanxi, 0351, China
The First Affiliated Hospital of Xi'an Jiaotong University
Xi’an, Shanxi, 029, China
Xi'an NO.3 Hospital
Xi’an, Shanxi, 029, China
West China Hospital of Sichuan University
Chengdu, Sichuan, 028, China
Zhejiang Hospital
Hangzhou, Zhejiang, 0571, China
Related Publications (1)
An X, Dong H, Deng Y, Chen Y, Zou Y, Zhang W, Jiang X. Evaluation of the role of combining inter-arm systolic pressure difference and derivatives of pulse volume recording in detecting subclavian artery stenosis. Front Cardiovasc Med. 2022 Sep 15;9:962610. doi: 10.3389/fcvm.2022.962610. eCollection 2022.
PMID: 36186962DERIVED
Study Officials
- PRINCIPAL INVESTIGATOR
Xiongjing Jiang, MD
Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 5 Years
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
April 11, 2018
First Posted
May 11, 2018
Study Start
January 1, 2018
Primary Completion
December 31, 2022
Study Completion
December 31, 2023
Last Updated
May 11, 2018
Record last verified: 2018-04
Data Sharing
- IPD Sharing
- Will not share