A Prospective Study on The"Management of Hypertension in Young and Middle-aged Subjects in Enterprises Setting"

NCT04135911 | Suspended

• 1 other identifier: PROMISE20190831
• Study Type: observational
• Target: 2,000
• Locations: 1 country
• Sites: 1

Brief Summary

In recent years, with the investment from government in the health management of the elderly, community management of hypertension in the elderly has made great progress in management rate and standardized management, but the management of young and middle-aged patients with hypertension is still blank. Workplace pressure measurement may be more suitable for most of the young and middle-aged patients to find high blood pressure and monitor blood pressure changes in time. However, there is not much research on workplace pressure measurement. Whether blood pressure measurement in the workplace can reduce the white coat effect, and how it relates to home blood pressure and ambulatory blood pressure is still unclear.

Conditions

Hypertension; Blood Pressure

Outcome Measures

Primary Outcomes (1)

• Diagnostic classification in hypertension

  Differences in diagnostic classification between workplace blood pressure and daytime ambulatory blood pressure in the classification of hypertension (masked hypertension or white coat hypertension)

  2 years

Secondary Outcomes (5)

• Change in different blood pressure measurement

  2 years

• The distribution of heart rate in young and middle-aged subjects

  2 years

• Progression of target organ damage

  2 years

• The development of with-coat hypertension

  2 years

• The proportion of masked hypertension in patients with normal high blood pressure

  2 years

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients measuring blood pressure at the workplace with normal high blood pressure or hypertensive patients.

You may qualify if:

• Male and female sex, aged 18-65 years
• Three different daytime workplace blood pressure measurements meet the limits: systolic blood pressure ≥ 120 mmHg, or diastolic blood pressure ≥80 mmHg
• Hypertensive patients who are taking antihypertensive drugs
• Willing to provide information about disease history and lifestyle
• Willing to receive follow-up for up to 2-3 years
• Sign the informed consent

You may not qualify if:

• Having the onset of cardiovascular and cerebrovascular diseases such as stroke, myocardial infarction or heart failure within 6 months
• Having a history of atrial fibrillation or frequent arrhythmia
• Complicating other diseases that are not suitable for the trial, such as thyroid disease with active medication, acute infectious diseases, chronic mental illness, and tumors
• The subject is participating in other clinical studies.

Sponsors & Collaborators

• Yan Li: lead

Study Sites (1)

Ruijin Hospital

Shanghai, Shanghai Municipality, 200025, China

Location

MeSH Terms

Conditions

Hypertension

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 2 Years
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Professor of Cardiovascular Medicine

Study Record Dates

• First Submitted: October 21, 2019
• First Posted: October 23, 2019
• Study Start: December 30, 2019
• Primary Completion: March 31, 2026
• Study Completion: March 31, 2026
• Last Updated: January 9, 2025

Record last verified: 2025-01

Locations

CN (1)