Correlational and Intervention Effects of Egg Consumption on Macular Carotenoids, Cognition, and Achievement During Childhood
SHELL
1 other identifier
interventional
80
1 country
1
Brief Summary
The aim of this study is to examine the correlational and intervention effects of egg consumption on macular carotenoids, cognition, and achievement during childhood. Initially, this will be done with correlational examination of egg consumption and macular carotenoids. Individuals with low carotenoid status will be invited to participant in a month-long egg-based dietary intervention aimed at improving carotenoid status.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Mar 2018
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 21, 2018
CompletedFirst Submitted
Initial submission to the registry
April 28, 2018
CompletedFirst Posted
Study publicly available on registry
May 11, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 1, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2020
CompletedApril 15, 2020
April 1, 2020
2.5 years
April 28, 2018
April 13, 2020
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Cognitive control
Changes in Cognitive Task Performance between Groups
1 month
Secondary Outcomes (1)
Macular Pigment Optical Density (MPOD)
1 month
Study Arms (2)
Egg White Snacks
PLACEBO COMPARATOREgg white-based snacks
Whole Egg Snacks
EXPERIMENTALWhole egg-based snacks
Interventions
Participants will consume an isocaloric muffin containing important bioactives from whole eggs.
Participants will consume an isocaloric muffin containing egg white, lacking important bioactives from whole eggs.
Eligibility Criteria
You may qualify if:
- a. Parental/guardian consent b. Between 7-12 years c. Absence of physician diagnosis of autism spectrum disorder d. Normal or corrected-to-normal vision based on the minimal 20/20 standard f. Intervention Only: Absence of food allergies
You may not qualify if:
- a. Parental/guardian non-consent b. Younger than 7 years or older than 12 years c. Physician diagnosis of autism spectrum disorder d. Uncorrected vision f. Intervention Only: Presence of food allergies
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- University of Illinois at Urbana-Champaignlead
- Egg Nutrition Centercollaborator
Study Sites (1)
University of Illinois
Urbana, Illinois, 61801, United States
Related Publications (1)
Liu R, Edwards CG, Cannavale CN, Flemming IR, Chojnacki MR, Reeser GE, Iwinski SJ, Renzi-Hammond LM, Khan NA. Weight Status and Visceral Adiposity Mediate the Relation between Exclusive Breastfeeding Duration and Skin Carotenoids in Later Childhood. Curr Dev Nutr. 2021 Feb 15;5(3):nzab010. doi: 10.1093/cdn/nzab010. eCollection 2021 Mar.
PMID: 33758790DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Naiman Khan, PhD, RD
University of Illinois at Urbana-Champaign
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- OTHER
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Naiman Khan, PhD, RD
Study Record Dates
First Submitted
April 28, 2018
First Posted
May 11, 2018
Study Start
March 21, 2018
Primary Completion
September 1, 2020
Study Completion
September 1, 2020
Last Updated
April 15, 2020
Record last verified: 2020-04
Data Sharing
- IPD Sharing
- Will share
Results will be disseminated by journal articles, thesis or academic papers, conference presentations, and sharing with the funding organization. No subject's identity will be disclosed in any presentation or released without their written permission.