NCT03514082

Brief Summary

Adolescent Idiopathic Scoliosis (AIS) is a rotational deformity of the spine that could be seen 2-3% of population. Conservative treatment of AIS with 20-45 degree lateral flexion angle (Cobb) includes brace and therapeutic exercises. Some gait abnormalities were defined like decreased torsional movements of spine, increased muscular work and energy expenditure in AIS. Additionally wearing a brace limits pelvic motions and affects pendulum-like mechanism of gait. Our aim was to investigate gait energy consumption, pulmonary functions, balance and lower extremity loading symmetry in AIS subjects who are getting conservative treatment.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
15

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Apr 2018

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 15, 2018

Completed
5 days until next milestone

First Submitted

Initial submission to the registry

April 20, 2018

Completed
12 days until next milestone

First Posted

Study publicly available on registry

May 2, 2018

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 15, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 15, 2019

Completed
Last Updated

January 31, 2019

Status Verified

January 1, 2019

Enrollment Period

9 months

First QC Date

April 20, 2018

Last Update Submit

January 30, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • Gait Oxygen Consumption

    Oxygen consumption will be assessed with a mobile metabolic analyzer during walking on treadmill with 4 km/h gait speed. Recordings will be taken for 2 minutes after first 2 minutes of walking.

    Assessment will be done at the end of first month of conservative treatment.

Secondary Outcomes (3)

  • Pulmonary Functions

    Assessment will be done at the end of first month of conservative treatment.

  • Balance

    Assessment will be done at the end of first month of conservative treatment.

  • Lower extremity loading symmetry

    Assessment will be done at the end of first month of conservative treatment.

Study Arms (1)

Adolescent Idiopathic Scoliosis

Subjects with AIS who are beginning to the conservative treatment.

Device: Rigid Thermoplastic Spinal Brace

Interventions

Custom made rigid thermoplastic brace with 23 hours daily wearing time.

Adolescent Idiopathic Scoliosis

Eligibility Criteria

Age10 Years - 16 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

Subject who come to our outpatient clinic will be assessed for eligibility.

You may qualify if:

  • Cobb angle between 20-45 degree,
  • Prescribed a rigid spinal brace by doctor

You may not qualify if:

  • Having leg length discrepancy more than 1 centimeter
  • Having a lung disease
  • Having another orthopedic or neurologic disorder

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Eastern Mediterranean University

Mersin, Famagusta, 99628, Turkey (Türkiye)

Location

Study Officials

  • Yasin Yurt, Asst. Prof.

    Eastern Mediterranean University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

April 20, 2018

First Posted

May 2, 2018

Study Start

April 15, 2018

Primary Completion

January 15, 2019

Study Completion

January 15, 2019

Last Updated

January 31, 2019

Record last verified: 2019-01

Data Sharing

IPD Sharing
Will not share

Locations