NCT03507283

Brief Summary

15 eyes of 15 patients with primary double-headed pterygia that underwent vertical split conjunctival autograft pterygium surgery were retrospectively reviewed. All patients had primary double-headed pterygia. Recurrence was defined as fibrovascular proliferation over the limbus onto the cornea. Vertical split conjunctival autograft using fibrin glue is an effective technique with good cosmetic results and low to no recurrence for primary double head pterygia treatment.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
15

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Apr 2011

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2011

Completed
5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2016

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2016

Completed
1.7 years until next milestone

First Submitted

Initial submission to the registry

April 15, 2018

Completed
10 days until next milestone

First Posted

Study publicly available on registry

April 25, 2018

Completed
Last Updated

April 26, 2018

Status Verified

April 1, 2018

Enrollment Period

5 years

First QC Date

April 15, 2018

Last Update Submit

April 24, 2018

Conditions

Pterygium of Conjunctiva and Cornea

Keywords

Pterygiumdouble-headedvertical

Outcome Measures

Primary Outcomes (1)

  • The recurrence rate

    fibrovascular tissue invading the cornea and expressed as a percentage

    1 year

Interventions

Double head pterygia excision and repairPROCEDURE

Complete excision of the pterygia was done. A free conjunctival autograft was obtained. The graft was divided vertically into two parts then secured into conjunctival defects.

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

This study included 15 eyes of 15 patients. The mean age of all patients was 36.92 ± 10.8 years. There were 9 males (60%) and 6 females (40%).

You may qualify if:

  • Primary double-headed pterygia

You may not qualify if:

  • NONE

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Elhamaky TR, Elbarky AM. Outcomes of Vertical Split Conjunctival Autograft Using Fibrin Glue in Treatment of Primary Double-Headed Pterygia. J Ophthalmol. 2018 Dec 20;2018:9341846. doi: 10.1155/2018/9341846. eCollection 2018.

    PMID: 30671262DERIVED

MeSH Terms

Conditions

Pterygium Of Conjunctiva And CorneaPterygium

Interventions

Wound Healing

Condition Hierarchy (Ancestors)

Conjunctival DiseasesEye Diseases

Intervention Hierarchy (Ancestors)

RegenerationBiological Phenomena

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
lecturer of ophthalmology

Study Record Dates

First Submitted

April 15, 2018

First Posted

April 25, 2018

Study Start

April 1, 2011

Primary Completion

April 1, 2016

Study Completion

August 1, 2016

Last Updated

April 26, 2018

Record last verified: 2018-04

Data Sharing

IPD Sharing
Will not share