Community Home-based Care Intervention and Its Health Outcome in HIV-positive People

NCT03505866 | Completed DMC

• 1 other identifier: 1523
• Study Type: interventional
• Target: 720
• Locations: 0 countries
• Sites: N/A

Brief Summary

An intervention study was designed to examine the impact of impact of community home-based care intervention on mental health and treatment outcome in HIV-positive people. The intervention comprised a home-based counseling on anti-retroviral therapy (ART) adherence, psycho social support, basic health care services at the home of HIV-positive people. The intervention started in March, 2018 and completed in August 2018. The major measurements of the interventions were ART adherence, status of depression, anxiety, and stress levels.

Conditions

Human Immunodeficiency Virus; Depression; Stress; Anxiety; Quality of Life

Keywords

HIV; Anti-retroviral therapy; Intervention; Mental Health

Outcome Measures

Primary Outcomes (4)

• Depression

  Depression was measured using a Center for Epidemiologic Studies Depression (CESD) scale. This scale consists of 20 items that are designed to measure the participant's experience of depressive symptoms in the past week of data collection. The total scores range from 0 to 60, and, a cut off point was set as scores ≥ 16 designating the occurrence of depressives symptoms.

  6 months

• Anti-retroviral therapy non-adherence

  Adherence to anti-retroviral therapy was measured using AIDS Clinical Trial Group Questionnaires. The questionnaires are designed to measure non-adherence whether the HIV-positive person missed at least one dose of anti-retroviral therapy in the past month of the data collection. The questionnaire assess

  6 months

• Anxiety

  Anxiety was measured anxiety using Composite International Diagnostic Interview Short-Form (CIDI-SF) the scale use nine screening stem questions that were designed to measure the episodes of anxiety and their control over their worries and anxious state.

  6 months

• stress

  Stress was in the past month using the Perceived Stress Scale (PSS). It consists of 10 items with scores ranging from "0" (never) to 4 (very often). The total score ranges from 0-40. Higher stress scores indicate high level of stress.

  6 months

Study Arms (1)

Mutual support groups of HIV

OTHER

HIV-positive people who did not enroll in a community home-based care intervention and receiving regular HIV services and support from mutual support groups of HIV

Behavioral: Community home-based care intervention

Interventions

Community home-based care intervention BEHAVIORAL

HIV-positive people who received community home-based care intervention on a monthly basis for six months after they enrolled in the program.

Mutual support groups of HIV

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• HIV-positive people who did not enroll in a community home-based care program before the baseline data collection for intervention. Those who were referred by an ART center or a voluntary counseling and testing center for care and support services
• Those who were diagnosed as HIV-positive within five years of baseline data collection and living in the selected districts for at least one year
• Those who received pre-ART counseling services and were receiving ART for at least one year
• Those who voluntarily agreed to enroll in a community home-based care program and received intervention after the baseline study.

Sponsors & Collaborators

• Integrated Development Foundation Nepal: lead
• Tokyo University: collaborator

Related Publications (1)

• Pokhrel KN, Sharma VD, Pokhrel KG, Neupane SR, Mlunde LB, Poudel KC, Jimba M. Investigating the impact of a community home-based care on mental health and anti-retroviral therapy adherence in people living with HIV in Nepal: a community intervention study. BMC Infect Dis. 2018 Jun 7;18(1):263. doi: 10.1186/s12879-018-3170-1.

  PMID: 29879916 DERIVED

MeSH Terms

Conditions

Acquired Immunodeficiency Syndrome; Depression; Anxiety Disorders; Psychological Well-Being

Condition Hierarchy (Ancestors)

HIV Infections; Blood-Borne Infections; Communicable Diseases; Infections; Sexually Transmitted Diseases, Viral; Sexually Transmitted Diseases; Lentivirus Infections; Retroviridae Infections; RNA Virus Infections; Virus Diseases; Slow Virus Diseases; Genital Diseases; Urogenital Diseases; Immunologic Deficiency Syndromes; Immune System Diseases; Behavioral Symptoms; Behavior; Mental Disorders; Personal Satisfaction

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Research and Program Development Advisor

Model Details: The intervention was started in February and March, 2015 and was completed six month later. The program comprises of psychosocial support/peer counseling, ART adherence support and counseling, basic health care, and referral for further care. The support team comprises of a community health worker, a trained HIV-positive person, and a social worker.

Study Record Dates

• First Submitted: April 1, 2018
• First Posted: April 23, 2018
• Study Start: March 1, 2015
• Primary Completion: August 31, 2015
• Study Completion: August 31, 2015
• Last Updated: April 24, 2018

Record last verified: 2018-04