NCT03500926

Brief Summary

This randomized controlled trial will compare patients receiving a standard uncemented femoral stem with patients receiving an identically designed short uncemented femoral stem.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
160

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Mar 2018

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 9, 2018

Completed
Same day until next milestone

Study Start

First participant enrolled

March 9, 2018

Completed
1 month until next milestone

First Posted

Study publicly available on registry

April 18, 2018

Completed
3.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 9, 2022

Completed
3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

March 9, 2025

Completed
Last Updated

April 18, 2018

Status Verified

March 1, 2018

Enrollment Period

4 years

First QC Date

March 9, 2018

Last Update Submit

April 10, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • stem subsidence

    stem subsidence will be measured using the EBRA (Ein-Bild-Rontgen-analyse) software on postoperative antero-posterior radiographs (5 xrays from day one to year 2)

    2 years postop

Secondary Outcomes (1)

  • Intraoperative surgeon satisfaction

    intraoperative

Other Outcomes (12)

  • intraoperative proportion of patients requiring a blood transfusion

    at time of hospital discharge, at approximately 2 days

  • postoperative PMA (Postel Merle d'Aubigné) score after hospital discharge

    3 months, 1 year, 2 years, 5 years

  • postoperative Oxford hip score after hospital discharge

    3 months, 1 year, 2 years, 5 years

  • +9 more other outcomes

Study Arms (2)

hype standard

ACTIVE COMPARATOR

total hip replacement with standard femoral stem

Device: total hip replacement - standard femoral stem

hype mini

EXPERIMENTAL

total hip replacement with short uncemented femoral stem

Device: total hip replacement - short femoral stem

Interventions

total hip replacement with standard femoral stem

hype standard

total hip replacement with short femoral stem

hype mini

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • hip osteoarthritis requiring a total hip replacement
  • \>18 years old
  • agrees to participate

You may not qualify if:

  • total hip replacement not indicated
  • general anesthesia contraindicated
  • previous surgery on the ipsilateral femur
  • follow-up not possible

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hopital Cochin

Paris, Île-de-France Region, 75014, France

RECRUITING

MeSH Terms

Conditions

Osteoarthritis, Hip

Condition Hierarchy (Ancestors)

OsteoarthritisArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic Diseases

Study Officials

  • David BIAU, MD

    Association pour le Développement et l'Enseignement de la Chirurgie Réparatrice et Orthopédique

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Masking Details
implant
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: randomized 1/1 comparison
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

March 9, 2018

First Posted

April 18, 2018

Study Start

March 9, 2018

Primary Completion

March 9, 2022

Study Completion

March 9, 2025

Last Updated

April 18, 2018

Record last verified: 2018-03

Locations