Diagnosis of Acquired Punctal Stenosis Using Anterior Segment Optical Coherence Tomography
Evaluation of Acquired Punctal Stenosis by Using Anterior Segment Optical Coherence Tomography (AS-OCT)
1 other identifier
observational
60
0 countries
N/A
Brief Summary
Purpose of the study To evaluate the lower puntum dimensions in cases of acquired punctal stenosis(APS), using anterior segment optical coherence tomography (AS-OCT).
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started May 2018
Shorter than P25 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 2, 2018
CompletedFirst Posted
Study publicly available on registry
April 13, 2018
CompletedStudy Start
First participant enrolled
May 1, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
July 1, 2018
CompletedApril 13, 2018
April 1, 2018
1 month
April 2, 2018
April 6, 2018
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Lower punctum dimensions in cases with acquired punctual stenosis, compared with lower punctal dimensions in normal subjects
External punctum diameter measured in µm, internal punctum diameter, measured in µ m, punctal depth measured in µ m
one month
Study Arms (2)
Patients with acquired punctal stenosis
Patients with acquired punctal stenosis with epiphora
Control subjects
normal subjects, without evidence of any punctal abnormalities.
Interventions
lower punctum examination by AS-OCT
Eligibility Criteria
Adults with acquired punctal stenosis
You may qualify if:
- Patients with acquired punctal stenosis
You may not qualify if:
- Punctal agenesis
- Congenital punctal stenosis
- Allergic occlusion
- Lid malposition
- Canalicular, nasolacrimal, sac and duct obstruction
- Previous eyelid or lacrimal drainage surgery
- Untreated conjunctivitis, blepharitis
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Minia Universitylead
Related Publications (4)
Soiberman U, Kakizaki H, Selva D, Leibovitch I. Punctal stenosis: definition, diagnosis, and treatment. Clin Ophthalmol. 2012;6:1011-8. doi: 10.2147/OPTH.S31904. Epub 2012 Jul 3.
PMID: 22848141BACKGROUNDKakizaki H, Takahashi Y, Iwaki M, Nakano T, Asamoto K, Ikeda H, Goto E, Selva D, Leibovitch I. Punctal and canalicular anatomy: implications for canalicular occlusion in severe dry eye. Am J Ophthalmol. 2012 Feb;153(2):229-237.e1. doi: 10.1016/j.ajo.2011.07.010. Epub 2011 Oct 6.
PMID: 21982102BACKGROUNDKashkouli MB, Pakdel F, Kiavash V. Assessment and management of proximal and incomplete symptomatic obstruction of the lacrimal drainage system. Middle East Afr J Ophthalmol. 2012 Jan;19(1):60-9. doi: 10.4103/0974-9233.92117.
PMID: 22346116BACKGROUNDWawrzynski JR, Smith J, Sharma A, Saleh GM. Optical coherence tomography imaging of the proximal lacrimal system. Orbit. 2014 Dec;33(6):428-32. doi: 10.3109/01676830.2014.949793. Epub 2014 Sep 12.
PMID: 25215411BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Lecturer of Ophthalmology/ Ophthalmology department/Faculty of Medicine/(Principal Investigator)
Study Record Dates
First Submitted
April 2, 2018
First Posted
April 13, 2018
Study Start
May 1, 2018
Primary Completion
June 1, 2018
Study Completion
July 1, 2018
Last Updated
April 13, 2018
Record last verified: 2018-04
Data Sharing
- IPD Sharing
- Will not share