Comparisonbetween Primary Hypertension Monitoring Methods for Detection of Early Kidney Dysfunction

NCT03491813 | Unknown

• 1 other identifier: Hypertension and CKD
• Study Type: observational
• Target: 102
• Locations: 0 countries
• Sites: N/A

Brief Summary

The present study aims to show the difference of blood pressure monitored centrally and automated BP monitoring among patients with primary hypertension for early detection of kidney dysfunction

Conditions

Primary Hypertension

Outcome Measures

Primary Outcomes (1)

• Detection of kidney dysfunction in patients with primary hypertension

  Detection of kidney dysfunction by estimation of creatinine clearance using crclcockroftـGault equation. In patients with primary hypertension and blood pressure will measured by two methods 1. Central Blood Pressure monitoring through non-invasively using a new well calibrated device named Mobil-O- Graph .( Cuff-based oscillometry at the brachial artery) 2. Automatic blood pressure monitor (Oscillometric) named the OMRON M2 basic® device was provided by Omron Healthcare company.

  1 year

Interventions

oscillometric device DEVICE

The blood pressure will be measured by the Automatic blood pressure monitor(Oscillometric) named the OMRON M2 basic® device was provided by Omron Healthcare company. This monitor uses inflation by Fuzzy-Logic controlled by electric pump and an automatic rapid pressure release valve for the deflation , its cuff allows BP measurements in arm circumference of 22-42 cm. The device measure BP and pulse rate with a pressure range of 0-299 mmHg and pulse rate range of 40-180 beats/min.

Eligibility Criteria

• Age: 40 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study will include patients with primary hypertension.

You may qualify if:

• Age between 40 Years to 70 Years old .
• Patients who have history of primary hypertension either on medical treatment or not .

You may not qualify if:

• All patients with 2ry hypertension.
• Diabetic patients.
• Patients with ESRD on regular dialysis .
• Patients with creatinineclearance \>30ml/min .
• collagen diseases

Sponsors & Collaborators

• Assiut University: lead

Related Publications (3)

• Cornoni-Huntley J, LaCroix AZ, Havlik RJ. Race and sex differentials in the impact of hypertension in the United States. The National Health and Nutrition Examination Survey I Epidemiologic Follow-up Study. Arch Intern Med. 1989 Apr;149(4):780-8.

  PMID: 2784957 BACKGROUND

• Burt VL, Whelton P, Roccella EJ, Brown C, Cutler JA, Higgins M, Horan MJ, Labarthe D. Prevalence of hypertension in the US adult population. Results from the Third National Health and Nutrition Examination Survey, 1988-1991. Hypertension. 1995 Mar;25(3):305-13. doi: 10.1161/01.hyp.25.3.305.

  PMID: 7875754 BACKGROUND

• Pickering T. The case for a hybrid sphygmomanometer. Blood Press Monit. 2001 Aug;6(4):177-9. doi: 10.1097/00126097-200108000-00002.

  PMID: 11805464 BACKGROUND

MeSH Terms

Conditions

Essential Hypertension

Condition Hierarchy (Ancestors)

Hypertension; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Ahmed Abdel Galeel, MD

  Assiut University

  STUDY CHAIR

• Doaa Fouad

  Assiut University

  STUDY DIRECTOR

Central Study Contacts

Nader Fawzy, MB Bch

CONTACT

00201200394430; nader.nabilfawzy87@gmail.com

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: March 19, 2018
• First Posted: April 9, 2018
• Study Start: August 1, 2019
• Primary Completion: December 1, 2019
• Study Completion: June 1, 2020
• Last Updated: March 11, 2019

Record last verified: 2019-03