Assessment of Investigational Positron Emission Tomography and Post-Processing Procedures Performed as Add-ons to Standard of Care Imaging
1 other identifier
interventional
131
1 country
1
Brief Summary
The goals of this study are to (1) develop and refine PET post-processing acquisition procedures, (2) generate preliminary and comparative imaging data for potential clinical trials, and (3) retrospectively evaluate standard of care PET imaging acquisitions by comparison with investigational PET imaging acquisitions.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Jan 2015
Longer than P75 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 2, 2015
CompletedFirst Submitted
Initial submission to the registry
February 22, 2018
CompletedFirst Posted
Study publicly available on registry
April 6, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
December 31, 2024
CompletedJanuary 18, 2024
January 1, 2024
10 years
February 22, 2018
January 16, 2024
Conditions
Outcome Measures
Primary Outcomes (4)
image quality
assessed by blinded readers
through study completion, on average 2-5 years
artifacts
assessed by blinded readers
through study completion, on average 2-5 years
lesion detectability
assessed by blinded readers
through study completion, on average 2-5 years
image noise
assessed region of interest over target tissue and background
through study completion, on average 2-5 years
Study Arms (2)
Prospective population
EXPERIMENTALRetrospective population
EXPERIMENTALInterventions
Investigational PET scan as add-on to standard-of-care scan
Review of pre-existing data from January 1, 2001 through December 5, 2017
Eligibility Criteria
You may qualify if:
- Male and female volunteers greater than or equal to 18 years of age
- Patients receiving a standard of care PET scan at OSU
You may not qualify if:
- Participants who are pregnant or lactating
- Prisoners
- Subjects incapable of giving informed written consent
- Retrospective Population:
- Male and female patients greater than or equal to 18 years of age
- Patients who have previously received a standard of care PET scan at OSU
- None
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
The Ohio State University Wexner Medical Center
Columbus, Ohio, 43221, United States
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Michael V Knopp, MD, PhD
Ohio State University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- NONE
- Purpose
- DIAGNOSTIC
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
February 22, 2018
First Posted
April 6, 2018
Study Start
January 2, 2015
Primary Completion
December 31, 2024
Study Completion
December 31, 2024
Last Updated
January 18, 2024
Record last verified: 2024-01