NCT03488511

Brief Summary

Preoperative nutritional state is closely related to perioperative morbidity and complications. This study aims to determine the effect of a protein-rich meal service in the preoperative setting compared to usual care.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
126

participants targeted

Target at P50-P75 for not_applicable surgery

Timeline
Completed

Started Mar 2018

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 5, 2018

Completed
16 days until next milestone

First Submitted

Initial submission to the registry

March 21, 2018

Completed
15 days until next milestone

First Posted

Study publicly available on registry

April 5, 2018

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2019

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2019

Completed
Last Updated

February 19, 2020

Status Verified

April 1, 2019

Enrollment Period

1.2 years

First QC Date

March 21, 2018

Last Update Submit

February 17, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Protein intake relative to requirements

    3-day food diary filled in at baseline and after 3 weeks.

    3 weeks

Secondary Outcomes (9)

  • Nutritional status

    3 weeks

  • Quality of life and overall health status

    3 weeks

  • Patient satisfaction

    3 weeks

  • Length of stay

    2 months

  • Readmissions

    2 months

  • +4 more secondary outcomes

Study Arms (2)

Intervention group

EXPERIMENTAL

The intervention group will receive meals from FoodforCare at Home. The FoodforCare at Home concept consists of six small protein and energy enriched meals and snacks that will be delivered twice a week. After an individual intake, the composition of the dishes will be tailored to the needs of the patient in terms of composition, diet, taste, flavor and portion size. Besides the meals, patients in the intervention group will also receive an information leaflet about the importance of protein during treatment and how to reach their protein requirements.

Other: FoodforCare at home

Control group

NO INTERVENTION

The control group will continue their usual diet for 3 weeks and have no restrictions to their diet.

Interventions

Six small protein rich meals that will be delivered twice a week for 3 weeks.

Intervention group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • years or older
  • surgical patients
  • living within a 40 km radius around Nijmegen/Veghel
  • surgery: Urology, Orthopedics, Gynaecology, General Surgery
  • oral intake

You may not qualify if:

  • renal insufficiency (MDRD-GFR (glomerular filtration rate) \< 60ml/min and/or proteinuria)\*
  • food allergy
  • planned vacation during intervention period
  • proteinuria is defined in case of a protein creatinine ratio \> 0.5g/10mmol or an albuminuria \> 300mg/day.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Radboudumc

Nijmegen, Gelderland, 6525 GA, Netherlands

Location

Maasziekenhuis Pantein

Beugen, North Brabant, 5835DV, Netherlands

Location

Study Officials

  • Manon van den Berg, PhD

    Radboud University Medical Center

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 21, 2018

First Posted

April 5, 2018

Study Start

March 5, 2018

Primary Completion

June 1, 2019

Study Completion

September 1, 2019

Last Updated

February 19, 2020

Record last verified: 2019-04

Data Sharing

IPD Sharing
Will not share

Locations