NCT03482986

Brief Summary

The purpose of the study is to test how dietary habit interventions affect patients weight loss outcomes after bariatric surgery.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
44

participants targeted

Target at P25-P50 for not_applicable

Timeline
26mo left

Started Dec 2021

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress67%
Dec 2021Jun 2028

First Submitted

Initial submission to the registry

March 12, 2018

Completed
17 days until next milestone

First Posted

Study publicly available on registry

March 29, 2018

Completed
3.7 years until next milestone

Study Start

First participant enrolled

December 7, 2021

Completed
6.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2028

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2028

Last Updated

December 5, 2025

Status Verified

November 1, 2025

Enrollment Period

6.6 years

First QC Date

March 12, 2018

Last Update Submit

November 28, 2025

Conditions

Keywords

DietDietary HabitsWeight changes

Outcome Measures

Primary Outcomes (1)

  • Post-intervention change in self-rated hunger

    Differences in self-rated hunger as measured from the visual analogue scale (VAS; 0-100 score with 0 as ''not at all'' and 100 as ''very much''/''extremely'') questionnaire at baseline and after the intervention

    Baseline and 4 weeks (post-intervention)

Secondary Outcomes (3)

  • Change in caloric intake

    baseline and 4 weeks (post-intervention)

  • Change in energy expenditure

    baseline and 4 weeks (post-intervention)

  • Change in glucose tolerance

    baseline and 4 weeks (post-intervention)

Study Arms (2)

Group A

EXPERIMENTAL

Subject will be advised to follow dietary habits plan A. Since this is a single blind study, the details of the dietary interventions cannot be released during recruitment stage, but will be made public once enrollment closes.

Behavioral: Dietary habits plan

Group B

EXPERIMENTAL

Subject will be advised to follow dietary habits plan B. Since this is a single blind study, the details of the dietary interventions cannot be released during recruitment stage, but will be made public once enrollment closes.

Behavioral: Dietary habits plan

Interventions

Patients will be given a personalized plan regarding their diet.

Group AGroup B

Eligibility Criteria

Age22 Years - 62 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Bariatric surgery (sleeve gastrectomy) patients

You may not qualify if:

  • Insulin-dependent diabetes
  • Anemia
  • Smoking
  • Shift work within the past 1 year
  • Drug or alcohol dependency
  • Bipolar disorder
  • Post traumatic stress disorder (PTSD)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Brigham and Women's Hospital

Boston, Massachusetts, 02115, United States

Location

MeSH Terms

Conditions

ObesityFeeding BehaviorBody Weight Changes

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and SymptomsBehavior, AnimalBehavior

Study Officials

  • Frank Scheer, PhD

    Brigham and Women's Hospital

    PRINCIPAL INVESTIGATOR
  • Ali Tavakkoli, MD

    Brigham and Women's Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor of Medicine

Study Record Dates

First Submitted

March 12, 2018

First Posted

March 29, 2018

Study Start

December 7, 2021

Primary Completion (Estimated)

June 30, 2028

Study Completion (Estimated)

June 30, 2028

Last Updated

December 5, 2025

Record last verified: 2025-11

Data Sharing

IPD Sharing
Will not share

Locations