Trichoscopy in Diagnosis of Immunobollous Diseases

NCT03478072 | Unknown

• 1 other identifier: AUEC
• Study Type: observational
• Target: 60
• Locations: 0 countries
• Sites: N/A

Brief Summary

Autoimmune bullous diseases are a variety of skin diseases that are characterized by the presence of bullae or blisters. Most of these diseases are associated with substantial morbidity and mortality. They are classified according to the site of blister formation into intraepidermal as pemphigus valgaris and foliaceus, and subepidermal as bullous pemphigoid and dermatitis herpetiformis. These lesions commonly affect the scalp and manifest as blisters, erosions and crustations. Trichoscopy (hair and scalp dermoscopy) is a non-invasive technique in which either a handheld dermoscope or a digital videodermoscope can be used to visualize hair and scalp structures. The method has well-established position as an ancillary tool in the diagnosis of many disorders such as, tinea capitis, alopecia areata, androgenetic alopecia, discoid lupus erythematosus, lichen planopilaris, folliculitis decalvans and other hair and scalp diseases. Few studies have reported that immunobullous diseases present characteristic trichoscopic patterns. So, Trichoscopy can be used as a rapid in-office preliminary diagnostic tool in the differential diagnosis of these diseases.

Conditions

IMMUNOBULLOUS DISEASES

Outcome Measures

Primary Outcomes (2)

• trichoscopic features of autoimmune bullous diseases and frequency of each feature.

  Detect trichoscopic features of autoimmune bullous diseases and frequency of each feature.

  1year

• diagnostic accuracy of trichoscopy in autoimmune bullous diseases.

  detect diagnostic accuracy of trichoscopy in autoimmune bullous diseases..

  1year

Interventions

trichoscopy DEVICE

hair and scalp dermoscopy) is a non-invasive technique in which either a handheld dermoscope or a digital videodermoscope can be used to visualize hair and scalp structures

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

upper Egyptian patients

You may qualify if:

• Patients with clinical \& histopathological diagnosis of autoimmune bullous diseases.

You may not qualify if:

• Patients who will not consent.
• Patients with any concomitant dermatological diseases.
• Pregnancy and lactation.

Sponsors & Collaborators

• tasbeeh salah: lead

Related Publications (2)

• Sar-Pomian M, Rudnicka L, Olszewska M. Trichoscopy - a useful tool in the preliminary differential diagnosis of autoimmune bullous diseases. Int J Dermatol. 2017 Oct;56(10):996-1002. doi: 10.1111/ijd.13725. Epub 2017 Aug 30.

  PMID: 28856676 RESULT

• Sar-Pomian M, Kurzeja M, Rudnicka L, Olszewska M. The value of trichoscopy in the differential diagnosis of scalp lesions in pemphigus vulgaris and pemphigus foliaceus. An Bras Dermatol. 2014 Nov-Dec;89(6):1007-12. doi: 10.1590/abd1806-4841.20143830.

  PMID: 25387515 RESULT

Study Officials

• Nagwa Easa, prof

  prof

  STUDY CHAIR

Central Study Contacts

Nagwa Easa, prof

CONTACT

01223971657; nagwaeasa@yahoo.com

Ayman Mahran, Lecturer

CONTACT

01009948311; aymanderma@yahoo.com

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: principal investigator

Study Record Dates

• First Submitted: March 15, 2018
• First Posted: March 27, 2018
• Study Start: December 1, 2018
• Primary Completion: December 1, 2019
• Study Completion: June 1, 2020
• Last Updated: July 30, 2018

Record last verified: 2018-07

Data Sharing

• IPD Sharing: Will not share