Relevance of Trichoscopy in Differential Diagnosis of Focal Non-cicatricial Alopecia in Children

NCT03260777 | Completed

• 1 other identifier: ROTIDDOFNCAIC
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Alopecia is a common, distressing condition that is sometimes difficult to diagnose and treat. Losing hair is not usually health threatening; it can scar a young child's vulnerable self-esteem by causing immense psychological and emotional stress, not only to the patient, but also to the concerned parents and siblings; so the cause of hair loss should be diagnosed and treated early to overcome the resulting problems.

Conditions

Focal Non-cicatricial Alopecia

Outcome Measures

Primary Outcomes (1)

• Sensitivity and specificity of the common trichoscopic findings in diagnosis of clinically difficult cases of focal non-cicatricial alopecia in children.

  Characteristic trichoscopic findings will be searched for in each case such as (exclamation mark hairs, yellow and black dots) for alopecia areata. Flame hairs, tulip hairs, coiled hairs, hook hairs, v-sign and irregularly broken hairs for trichotillomania.Findings for tinea capitis (comma hairs, zigzag hairs, corkscrew hairs and block hairs).Coiled irregularly broken hairs and hair casts for tractional alopecia.

  2017-2018

Study Arms (4)

children with Alopecia Areata

Device: Trichoscopy

children with tinea capitis

Device: Trichoscopy

children with trichotillomania

Device: Trichoscopy

children with tractional alopecia

Device: Trichoscopy

Interventions

Trichoscopy DEVICE

Trichoscopy (hair and scalp dermoscopy) is a noninvasive diagnostic tool that allows the recognition of morphologic structures not visible by the naked eye Structures which may be visualized by trichoscopy include hair shafts of different types, the number of hairs in one pilosebaceous unit, hair follicle openings (dots), the peri and interfollicular areas and the vasculature.

children with Alopecia Areata; children with tinea capitis; children with tractional alopecia; children with trichotillomania

Eligibility Criteria

• Age: 3 Years - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Probability Sample

Study Population

100 Patients with focal non-cicatricial alopecia will be recruited from the outpatient clinic of Dermatology , Venereology and Andrology department at Assiut University Hospital

You may qualify if:

• age from 3-18 years of both sexes with focal non-cicatricial alopecia.(1-5 patches of alopecia)

You may not qualify if:

• Patients who will not consent.
• uncooperative children.
• patients with active secondary bacterial infection in the alopecic patch.
• patients with any concomitant dermatological diseases.
• history of using any topical(1 month) or systemic treatment (3 month) for tinea capitis or alopecia areata prior to the study,
• cicatricial alopecia.

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Assiut Universuty

Asyut, 71515, Egypt

Location

Related Publications (5)

• Lencastre A, Tosti A. Role of trichoscopy in children's scalp and hair disorders. Pediatr Dermatol. 2013 Nov-Dec;30(6):674-82. doi: 10.1111/pde.12173. Epub 2013 Aug 13.

  PMID: 23937326 BACKGROUND

• Miteva M, Tosti A. Hair and scalp dermatoscopy. J Am Acad Dermatol. 2012 Nov;67(5):1040-8. doi: 10.1016/j.jaad.2012.02.013. Epub 2012 Mar 8.

  PMID: 22405573 BACKGROUND

• Sarifakioglu E, Yilmaz AE, Gorpelioglu C, Orun E. Prevalence of scalp disorders and hair loss in children. Cutis. 2012 Nov;90(5):225-9.

  PMID: 23270190 BACKGROUND

• Rakowska A. Trichoscopy (hair and scalp videodermoscopy) in the healthy female. Method standardization and norms for measurable parameters. J Dermatol Case Rep. 2009 Apr 5;3(1):14-9. doi: 10.3315/jdcr.2008.1021.

  PMID: 21886722 BACKGROUND

• Hillmann K, Blume-Peytavi U. Diagnosis of hair disorders. Semin Cutan Med Surg. 2009 Mar;28(1):33-8. doi: 10.1016/j.sder.2008.12.005.

  PMID: 19341940 BACKGROUND

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principle Investigator

Study Record Dates

• First Submitted: August 21, 2017
• First Posted: August 24, 2017
• Study Start: November 18, 2017
• Primary Completion: September 1, 2019
• Study Completion: September 1, 2019
• Last Updated: January 13, 2021

Record last verified: 2021-01

Locations

EG (1)