NCT03473678

Completed

Dietary Nitrate and Healthy Older Adults

University of Exeter Source

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Other study identifiers

Sponsor study identifier

121964

Study Type

interventional

Actual enrollment (reported)

30

Locations

1 country

Sites

1

Timeline

Study Start

February 12, 2014

Actual (reported)

Primary Completion

May 28, 2015

Actual (reported)

Study Completion

January 2018

Actual (reported)

Brief Summary

This study investigates the influence of dietary nitrate supplementation on cardiovascular health and physical and cognitive performance in older adults. Participants will receive both a nitrate containing beetroot juice for 10 days and a nitrate depleted beetroot juice for 10 days

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: completed
Actual enrollment (reported): 30 participants
Study completion date: January 2018
Actual (reported)
Listed locations: 1 countries · 1 sites

Trial Relationships

Click on a node to explore related trials.

Some registry-reported names shown below are not yet linked in this graph.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

Study Start
February 12, 2014
Actual (reported)
Primary Completion
May 28, 2015
Actual (reported)
Study Completion
January 2018
Actual (reported)
First Submitted
January 31, 2018
Actual (reported)
First Posted
March 22, 2018
Actual (reported)

Last Updated: March 22, 2018
Status Verified: March 2018
Last Update Submitted: March 14, 2018

Conditions

Blood Pressure Brain Metabolism Cognitive Change Functional Capacity

Outcome Measures

Primary Outcomes (1)

Blood pressure
Change in blood pressure between interventions
10 days

Secondary Outcomes (5)

Oxygen cost of exercise
10 days
Serial Subtraction test
10 days
Microbiome
10 days
Brain metabolism
10 days
6 minute walk test
10 days

Study Arms (2)

Nitrate-rich beetroot juice

ACTIVE COMPARATOR

2 x 70mL concentrated juice per day for 10 days

Dietary Supplement: Nitrate-rich beetroot juice

Nitrate-depleted beetroot juice

PLACEBO COMPARATOR

2 x 70mL concentrated juice per day for 10 days

Dietary Supplement: Nitrate-depleted beetroot juice

Interventions

Nitrate-rich beetroot juiceDietary supplement

concentrated beetroot juice

Nitrate-rich beetroot juice

Nitrate-depleted beetroot juiceDietary supplement

concentrated beetroot juice

Nitrate-depleted beetroot juice

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age70 Years - 80 Years

Sexall

Healthy VolunteersYes

Age GroupsOlder Adult (65+)

You may qualify if:

years of age
male or female

You may not qualify if:

Sponsors & Collaborators

University of Exeter
Otherlead

Study Sites (1)

Sport and Health Sciences, University of Exeter

Exeter, Devon, EX12LU, United Kingdom

Study Officials

Andrew M Jones, PhD
University of Exeter
PRINCIPAL INVESTIGATOR

Enrollment

30 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: not applicable
Allocation: RANDOMIZED
Masking: QUADRUPLE
Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose: OTHER
Intervention Model: CROSSOVER
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

January 31, 2018

First Posted

March 22, 2018

Study Start

February 12, 2014

Actual (reported)

NCT03449992

The Effects of Nitrate Supplementation on Elite Runners

Not ApplicableCompleted

NCT05514821

Inter-individual Variation in the Blood Pressure Lowering Effects of Dietary Nitrate

Not ApplicableCompleted

NCT06777459

Study of Nitrate-Rich Juice on Cognitive Function in Heavy Alcohol Drinkers: a Two-Stage Adaptive Design Real-World Clinical Trial

Not ApplicableNot Yet Recruiting

NCT03871777

Dietary Nitrate Intake in Vegetarians and Omnivores

Not ApplicableCompleted

NCT02223403

Effect of Nitrate-rich Beetroot Juice on Exercise Performance in Heart Failure Patients

Not ApplicableCompleted

NCT07242066

Effects of Dietary Nitrate and Vitamin C Co-supplementation on Blood Pressure and Endothelial Function in Overweight Individuals

Not ApplicableCompleted

involved in regular structured exercise
receiving medication for:
pulmonary conditions
cardiovascular conditions
metabolic conditions
musculoskeletal conditions
ulcerative colitis
renal disease

Contact the study team to confirm eligibility.

Primary Completion

May 28, 2015

Actual (reported)

Study Completion

January 2018

Actual (reported)

Last Updated

March 22, 2018

Record last verified: 2018-03

Source record

Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.

Source: ClinicalTrials.gov.

JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.

Registry identifier: NCT03473678
Data provider: ClinicalTrials.gov
Source updated: 2018-03-22
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:40:48 UTC

Locations

GB(1)

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (5)

Study Arms (2)

Nitrate-rich beetroot juice

Nitrate-depleted beetroot juice

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

Study Officials

Enrollment

Study Design

Study Record Dates

Source record

Locations