An eHealth Intervention for Obsessive Compulsive Disorder in Youth With Autism Spectrum Disorder

NCT03473080 | Completed

• 1 other identifier: BIP ASD/OCD pilot
• Study Type: interventional
• Target: 22
• Locations: 1 country
• Sites: 1

Brief Summary

This study is a feasibility study of Internet-delivered CBT for OCD in children and adolescents (7-17 years) with comorbid Autism Spectrum Disorder.

Conditions

Obsessive-Compulsive Disorder

Keywords

OCD; ASD; Obsessive Compulsive Disorder; Autism Spectrum Disorder; ICBT; eHealth; Internet; CBT; Pediatric; Adolescents; Children; Internet-delivered

Outcome Measures

Primary Outcomes (1)

• Children's Yale-Brown Obsessive Compulsive Scale

  Changein obsessions and compulsions will be measured as the total score on the scale.. Total score ranges from 0 to 40 points, a higher score indicates more severe OCD. The scale is rated by a clinician.

  Baseline, 16 weeks (= post treatment), 3 months after post treatment, 6 months after post treatment, 12 months after post treatment

Secondary Outcomes (17)

• Obsessive-compulsive inventory - child version

  Baseline, weekly during treatment, 16 weeks (= post treatment), 3 months after post treatment, 6 months after post treatment, 12 months after post treatment

• Autism spectrum quotient (AQ-10)

  Baseline

• Education, work and social adjustment scale - child and parent version

  Baseline, 16 weeks (= post treatment), 3 months after post treatment, 6 months after post treatment, 12 months after post treatment

• Family accommodation scale for obsessive-compulsive disorder

  Baseline, 16 weeks (= post treatment), 3 months after post treatment, 6 months after post treatment, 12 months after post treatment

• Mood and Feeling Questionnaire - child and parent version

  Baseline, 16 weeks (= post treatment), 3 months after post treatment, 6 months after post treatment, 12 months after post treatment

Study Arms (1)

Internet CBT

OTHER

Participants and their parents receive 16 weeks of internet-delivered cognitive behavior therapy (CBT) with psychologist support.

Behavioral: Internet CBT

Interventions

Internet CBT BEHAVIORAL

The treatment consists of a standard cognitive behavior therapy for OCD with additional treatment components to make the treatment better suited for children and adolescents with Autism Spectrum Disorder.

Also known as: ICBT, Internet-delivered Cognitive Behavior Therapy

Internet CBT

Eligibility Criteria

• Age: 7 Years - 17 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• a diagnosis of OCD according to DSM-5
• a diagnosis of autism according to DSM-IV or DSM-5, confirmed with the Autism Diagnostic Interview- Revised or Autism Diagnostic Observation Schedule version 1 or 2 and by medical records
• a total score of ≥ 16 on the Children's Yale-Brown Obsessive-Compulsive Scale
• age between 7 and 17 years
• ability to read and write Swedish
• access to the internet
• a parent that is able to co-participate in the treatment
• participants on psychotropic medication must have been on a stable dose for the last 6 weeks prior to baseline assessment

You may not qualify if:

• a diagnosis of psychosis, bipolar disorder, severe eating disorder or intellectual disabilities
• comorbid hoarding disorder or OCD with hoarding as a principal symptom.
• suicidal ideation
• subject not able to read or understand the basics of the ICBT material
• completed CBT for OCD within last 12 months (defined as at least 5 sessions of CBT including exposure and response prevention)
• ongoing psychological treatment for OCD or any anxiety disorder
• OCD treatment is not an immediate priority

Sponsors & Collaborators

• Karolinska Institutet: lead

Study Sites (1)

BUP OCD and Related Disorders

Stockholm, 11330, Sweden

Location

MeSH Terms

Conditions

Obsessive-Compulsive Disorder; Autism Spectrum Disorder

Condition Hierarchy (Ancestors)

Anxiety Disorders; Mental Disorders; Child Development Disorders, Pervasive; Neurodevelopmental Disorders

Study Officials

• Fabian Lenhard, PhD

  Karolinska Institutet

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PhD, Principal Investigator

Study Record Dates

• First Submitted: February 16, 2018
• First Posted: March 22, 2018
• Study Start: March 9, 2018
• Primary Completion: February 15, 2021
• Study Completion: February 15, 2021
• Last Updated: July 6, 2021

Record last verified: 2021-07

Locations

SE (1)