Contrast Nephropathy in Type 2 Diabetes
VCG4
Prevalence of Contrast Nephropathy in Type 2 Diabetes Patients With Microalbuminuria
1 other identifier
observational
40
1 country
2
Brief Summary
To study the effect of radiocontrast material on kidney functions in diabetics with microalbuminuria
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Jul 2018
Shorter than P25 for all trials
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 9, 2018
CompletedFirst Posted
Study publicly available on registry
March 20, 2018
CompletedStudy Start
First participant enrolled
July 1, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 30, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
November 30, 2018
CompletedSeptember 16, 2020
September 1, 2020
3 months
March 9, 2018
September 12, 2020
Conditions
Outcome Measures
Primary Outcomes (1)
affection of estimated glomerular filtration rate
A significant decrease in estimated glomerular filtration rate (eGFR)
Two months
Secondary Outcomes (1)
change in serum uric acid
Two months
Other Outcomes (1)
Affection of albumin creatinine ratio
Two months
Study Arms (2)
diabetics on linagelptin
Diabetic patients were given linagelptin for blood glucose control
diabetics on other DPP4 inhibitors
Diabetic pateints were given other DPP4 inhibitors eg: vlidagliptin for blood glucose control
Interventions
Linagliptin for blood glucose control
Eligibility Criteria
Diabetics undergoing any intervention using radiocontrast material for any medical indication in Fayoum university hospital will be selected.
You may qualify if:
- Diabetics on DPP 4 inhibitor treatment
You may not qualify if:
- Diabetics on insulin
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Fayoum Universitylead
- Boehringer Ingelheimcollaborator
Study Sites (2)
Faculty of medicine Fayoum univesity
Al Fayyum, Egypt
Fayoum University
Al Fayyum, Egypt
Related Publications (1)
Fayed A, Hammad AA, Abdulazim DO, Hammad H, Amin M, Elhadidy S, Salem MM, ElAzim IMA, Zsom L, Csongradi E, Soliman KM, Sharaf El Din UA. Is the combination of linagliptin and allopurinol better prophylaxis against post-contrast acute kidney injury? A multicenter prospective randomized controlled study. Ren Fail. 2023 Dec;45(1):2194434. doi: 10.1080/0886022X.2023.2194434.
PMID: 36974638DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Usama A Sharafeldin, MD
Cairo University
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- CROSS SECTIONAL
- Target Duration
- 1 Week
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Lecturer of internal medicine
Study Record Dates
First Submitted
March 9, 2018
First Posted
March 20, 2018
Study Start
July 1, 2018
Primary Completion
September 30, 2018
Study Completion
November 30, 2018
Last Updated
September 16, 2020
Record last verified: 2020-09